I believe my tolerance is already pretty low and am mainly a microdoser. When I exclusively vape ACDC, which is 20% CBD & 1% THC or CBD tincture, I do not feel that it sets my THC tolerance even lower. That being said, I usually only vape from .05mg to .075mg a day which is a recent increase from my typical .04mg a day. I had to increase as I had a few breakthrough seizures. Everyone is different so what doesn’t work for me may work wonders for you. If your tolerance is high and you want to reset your system, Dr Dustin Sulak recommends that you only need to abstain from cannabis for 48 hours to lower your tolerance. His free video program which discusses this is at www.healer.com Wishing you the best!