It really depends on the effect you're chasing. Higher temps tend to be better for evening and bed time. And lower temps tend to be preferred during the day. People tend to bump the temp up a little if they are using a water pipe. A higher temp is also used with concentrates but the Solo is primarily a dry herb device. For the most part I keep the temp at 205 C and maybe bump it up to 210/215 with a water pipe. I believe most people would say the ability to go higher in temp is something they look for - but I'm not sure how many people are actually vaping that high. Regarding the cannabinoids - it's not like we can isolate a specific cannabinoid, but using the vaporization charts you can ensure you are getting the ones you want with everything else that is also able to vaporize at that temperature or lower. It will work the same way with any terpenes you are chasing as well.