Official CBD Discussion Thread

[shredder]

Do you guys think CBD and THC "cooperate" well (entourage, whatever you want to call it) only if ingested at the same time, or can you say, ingest full spectrum CBD in a vape, then load a THC strain and vape that immediately afterwards to the same effects?

ps I'm so disappointed in reading you need to take in 150-600mg CBD for social anxiety and other anxiety issues, according to a study linked around here often.

If 3.5g of good quality CBD flower is $30, those 3.5g would contain about 500-700mg of CBD. Meaning it's like $10-30 for one dose to be effective? That sounds... yeah

Maybe if consumed with THC it makes more sense? But CBD full spectrum flower now sounds bogus TBH

(full disclosure, only gleaned over that study, and it is one study. idk if lower doses were played with and ruled out or just not attempted, etc, but it's a study I see linked often)

You don't have to choose one or the other. There are thc strains that control anxiety pretty darn well. Try blue dream and or Colombian gold. Both help patients of mine deal with anxiety. For an indica try cherry pie, and you'll be a mellow fellow.

And yes you can mix thc and CBD with good effect. A pet peeve of mine is people thinking adding CBD takes something away from thc. IMHO it enhances the experience rather than take anything away.

can you somehow describe how the CBD effects you, opposed to THC?
(i would be more precise and say microdosing THC- not full blown high)
no exhaustion, as you said.. relaxing.

i ask because i mostly use THC to be creative at work or at evening,
and it makes me more peaceful and less negative.
and also for sleep.

and since getting genuine quality CBD stuff here is rare,
i thought of getting some CBD buds, and adding a bit THC when needed.

It's hard to define how you feel on CBD. A lot of us feel nothing definable, it's more like a lack of pain/inflammation than something you can spot. For me it's ussually later that I realize I did something and don't feel like I would have if I didn't have the CBD. That and I focus better when on CBD. Instead of wandering around in circles forgetting my next step while doing a project, (thc) I get right on it and stay focused when on CBD.

I often vaporize citrus oils during a cannabis session, would be interesting to compare the effects after olfactory stimulation of D-limonene in those essential oils. IIRC Russo says just smelling your cannabis is enough to stimulate the olfactory and modulate the effects/delivery of cannabinoids, so I always make a habit of getting a good whiff of whatever I plan to vaporize these days, just in case it helps modulate something!

It's hard to over estimate the role terpenes play. They may be the most important part, or at least an equal partner. If anyone askes about specific strains they might like, I ask what strains they like now, and suggest they research the terpene profile and go by that. For instance I don't care for the peppery or earthy tasting terpenes, but love the citrus or fruity types. Follow your nose, lol.

 

[rozroz]

It's hard to define how you feel on CBD. A lot of us feel nothing definable, it's more like a lack of pain/inflammation than something you can spot. For me it's ussually later that I realize I did something and don't feel like I would have if I didn't have the CBD. That and I focus better when on CBD. Instead of wandering around in circles forgetting my next step while doing a project, (thc) I get right on it and stay focused when on CBD.

so you can't tell if CBD effects general mood?

 

[shredder]

so you can't tell if CBD effects general mood?

My mood generally is good, I'm pretty easy going, and don't have anxiety, or depression so if it effects my mood I don't notice. We're all different though.

My issues are more nerve, muscle, and joint issues. For these issues it helps.

 

[C No Ego]

You don't have to choose one or the other. There are thc strains that control anxiety pretty darn well. Try blue dream and or Colombian gold. Both help patients of mine deal with anxiety. For an indica try cherry pie, and you'll be a mellow fellow.

And yes you can mix thc and CBD with good effect. A pet peeve of mine is people thinking adding CBD takes something away from thc. IMHO it enhances the experience rather than take anything away.



It's hard to define how you feel on CBD. A lot of us feel nothing definable, it's more like a lack of pain/inflammation than something you can spot. For me it's ussually later that I realize I did something and don't feel like I would have if I didn't have the CBD. That and I focus better when on CBD. Instead of wandering around in circles forgetting my next step while doing a project, (thc) I get right on it and stay focused when on CBD.



It's hard to over estimate the role terpenes play. They may be the most important part, or at least an equal partner. If anyone askes about specific strains they might like, I ask what strains they like now, and suggest they research the terpene profile and go by that. For instance I don't care for the peppery or earthy tasting terpenes, but love the citrus or fruity types. Follow your nose, lol.

the Terpenes are of most importance... phytocanabinoids are terpenes, they are monoterpenes... the smelly terpenes are sesquiterpenes . sesquiterpenes have longer half life then monoterpenes and that will direct the metabolic response .. volatile sesquiterpenes are the bio-chemical directors of the monoterpenes

 

[Abysmal Vapor]

Maybe it has been a week since i am using daily CBD isolate. Tried it naked, with terps, with herb ... This compound has synergy almost with everything i tried.
CBD + Carbonated soft drink containing Cola Nut extract 5% and Theobromine... It makes my heart beat like a hammer and for sure i had to decrease intake to half a bottle.. at a time... I am not a caffeine fan so ,maybe someone else would explore this..
CBD has synergy with Garlic and Ginseng.. probably it has something to do with their immunostimulant properties.
CBD alone... Compound brings a warm wave of pleasure which at lest with me turns into a stimulative phase,where i got all my sences sharpened. I get decreased appetite,almost forget about meals when i dive into the my daily job. This thing should be in Fitness formulas and in combination with Nootropics .Contatraty to the full spectrum herb effects ,i dont feel distracted or less willing to involve in working activities.. It makes you feel good without sending you on a mental vacation ).
At a later point the effects mellow into a stressfree state of mind.
CBD + terpenes... WOW... dabbing it,making carts.. it is just awesome. The terps i got were OG something... and are very energising,a lot of limonene notes there.I have yet to explore multiple combinations with other terps,but it makes a ton of difference compared to not having them.
At some point i will share more of my thoughts about it,but for now i thought i just post about my initial impressions..
One of the biggest Myths that was busted for me ,is that CBD brings you down/ sedate or brings Indika experience...This is a common misconception at least around here. I think CBN (Which is the compound responsible for the Lazyness) anda maybe the others ,i havent tried like CBG,but for sure CBD isnt.

 

[boocoodinkydow]

Maybe it has been a week since i am using daily CBD isolate. Tried it naked, with terps, with herb ... This compound has synergy almost with everything i tried.
CBD + Carbonated soft drink containing Cola Nut extract 5% and Theobromine... It makes my heart beat like a hammer and for sure i had to decrease intake to half a bottle.. at a time... I am not a caffeine fan so ,maybe someone else would explore this..
CBD has synergy with Garlic and Ginseng.. probably it has something to do with their immunostimulant properties.
CBD alone... Compound brings a warm wave of pleasure which at lest with me turns into a stimulative phase,where i got all my sences sharpened. I get decreased appetite,almost forget about meals when i dive into the my daily job. This thing should be in Fitness formulas and in combination with Nootropics .Contatraty to the full spectrum herb effects ,i dont feel distracted or less willing to involve in working activities.. It makes you feel good without sending you on a mental vacation ).
At a later point the effects mellow into a stressfree state of mind.
CBD + terpenes... WOW... dabbing it,making carts.. it is just awesome. The terps i got were OG something... and are very energising,a lot of limonene notes there.I have yet to explore multiple combinations with other terps,but it makes a ton of difference compared to not having them.
At some point i will share more of my thoughts about it,but for now i thought i just post about my initial impressions..
One of the biggest Myths that was busted for me ,is that CBD brings you down/ sedate or brings Indika experience...This is a common misconception at least around here. I think CBN (Which is the compound responsible for the Lazyness) anda maybe the others ,i havent tried like CBG,but for sure CBD isnt.

Interesting observations. Thanx for sharing.

I’ve recently started using a full spectrum cbd (.3% thc) infused MCT oil. I’m using it in capsule form in doses ranging from 15-50mg actual cbd. I’ve added a variety of terpene isolates with little modification in effects. It’s been very useful in combatting anxiety offering a very calming effect. Unfortunately, it has an accompanying lethargic effect as well. Motivation to accomplish even minor chores is challenging.

The results you’re experiencing with the cbd isolates is alluring and I think I may give it a go. I’ve often been faced with inconsistencies to others results due to anatomical diversity but sounds like it’s worth a try.

 

[fernand]

Watched a family member, who's on chemo w/ rather large doses of oral cannabis, try inverting the 8:1 THC:CBD ratio he's been using. The result was always stunningly terrible. Profound depression within hours, suicidal thoughts, no desire for anything, wooden expression and movements, and loss of the anti-nauseant protection of the THC. Like night vs. day. Dramatic.

To be specific, we're talking about an oral dose of 200mg CBD : 25mg THC, vs. the usual 250 mg THC : 30mg CBD taken twice to 3x daily. Same thing at 300mg : 40mg CBD:THC.

100mg of 25:1 CBD also seems to bring about a not-dramatic but wooden sedation in non-tolerant patients. This would be ~ 180 mg of a CBD rich AC/DC oil.

 

[boocoodinkydow]

Watched a family member, who's on chemo w/ rather large doses of oral cannabis, try inverting the 8:1 THC:CBD ratio he's been using. The result was always stunningly terrible. Profound depression within hours, suicidal thoughts, no desire for anything, wooden expression and movements, and loss of the anti-nauseant protection of the THC. Like night vs. day. Dramatic.

To be specific, we're talking about an oral dose of 200mg CBD : 25mg THC, vs. the usual 250 mg THC : 30mg CBD taken twice to 3x daily. Same thing at 300mg : 40mg CBD:THC.

100mg of 25:1 CBD also seems to bring about a not-dramatic but wooden sedation in non-tolerant patients. This would be ~ 180 mg of a CBD rich AC/DC oil.

Thanx for sharing.

In an effort to find a good relief for insomnia, I found larger doses of indica dominant strains caused unbearable depressive states throughout the night. My five year quest to find insomnia relief through many different forms of cannabis has ended in failure.

On a more positive note, I’ve recently started adding 1mg thc and 1mg of an uplifting mixture of terpene additives to 25mg of cbd and dosing twice per day for daytime use. Still not an utopian result but an improvement.

 

[3dfx-glide]

Thanx for sharing.

In an effort to find a good relief for insomnia, I found larger doses of indica dominant strains caused unbearable depressive states throughout the night. My five year quest to find insomnia relief through many different forms of cannabis has ended in failure.

On a more positive note, I’ve recently started adding 1mg thc and 1mg of an uplifting mixture of terpene additives to 25mg of cbd and dosing twice per day for daytime use. Still not an utopian result but an improvement.

have you tried going on a 2-5 day tolerance break and trying to micro dose?

 

[boocoodinkydow]

Actually I have recently abstained for nearly a month because of some digestive issues. But thanx for thr suggestion.

 

[archangelz001]

Watched a family member, who's on chemo w/ rather large doses of oral cannabis, try inverting the 8:1 THC:CBD ratio he's been using. The result was always stunningly terrible. Profound depression within hours, suicidal thoughts, no desire for anything, wooden expression and movements, and loss of the anti-nauseant protection of the THC. Like night vs. day. Dramatic.

To be specific, we're talking about an oral dose of 200mg CBD : 25mg THC, vs. the usual 250 mg THC : 30mg CBD taken twice to 3x daily. Same thing at 300mg : 40mg CBD:THC.

100mg of 25:1 CBD also seems to bring about a not-dramatic but wooden sedation in non-tolerant patients. This would be ~ 180 mg of a CBD rich AC/DC oil.

It sounds like the abrupt removal of a large dose of THC along with a sudden addition of a large dose of CBD may have had quite a bit to do with the resulting unwanted effects. Did someone with some credentials recommend that drastic change?

 

[fernand]

Did someone with some credentials recommend that drastic change?

Well, first of all, please don't take this as disrespectful, but allow me to ROFL about the "someone with some credentials". My own search for those has been heartbreakingly disappointing. Let me know if you find even a handful world-wide, if you mean someone with say an MD, oncology experience, and a plausible understanding of Cannabis effects on cancer. All the well-meaning pundits don't count any more than all the cannabis-hostile oncologists or the Rick Simpson fans. And it's worth noting that Rick Simpson never "cured himself of cancer", unless you consider a small basal cell carcinoma on his face equivalent to a stage 3 or 4 Big C.

To answer your implied question, "why", the reason was the same trial and error testing that's driven his rather successful treatment to date. I was reporting what we saw. Of course CBD's apparent antagonism of THC most likely plays a major role. The removal of THC is a less likely cause, since the reaction happened faster than THC is metabolized.

 

[Silat]

What are the favorite online shops for Terpenes?

 

[archangelz001]

Well, first of all, please don't take this as disrespectful, but allow me to ROFL about the "someone with some credentials". My own search for those has been heartbreakingly disappointing. Let me know if you find even a handful world-wide, if you mean someone with say an MD, oncology experience, and a plausible understanding of Cannabis effects on cancer. All the well-meaning pundits don't count any more than all the cannabis-hostile oncologists or the Rick Simpson fans. And it's worth noting that Rick Simpson never "cured himself of cancer", unless you consider a small basal cell carcinoma on his face equivalent to a stage 3 or 4 Big C.

To answer your implied question, "why", the reason was the same trial and error testing that's driven his rather successful treatment to date. I was reporting what we saw. Of course CBD's apparent antagonism of THC most likely plays a major role. The removal of THC is a less likely cause, since the reaction happened faster than THC is metabolized.

No disrespect taken ;-)

The reason I asked (in the THC break thread) is because I'm a retired RN and a member of the ACNA - American Cannabis Nurses Association - and am greatly interested in the evolving research on all things cannabis. You sound like an educated person and someone who has done quite a bit of research for yourself. The link you provided is good and you probably know that THC is an agonist at CB1 (in the central nervous system, primarily in the brain) and CB2 receptors (found distributed in the immune system the gut, spleen, liver, heart, kidneys, bones, blood vessels, lymph cells, endocrine glands and reproductive organs) while CBD is an antagonist. But how and why they affect cancer cells is still not clear. To say that CBD reverses or blocks the effect of THC at CB1 and CB2 receptors is true, but that doesn't explain the depressive features you observed.


Are you familiar with https://www.projectcbd.org/
or https://www.cannabisclinicians.org/directory/
Dr. Sulak's site is full of good information: https://healer.com/

FYI, I have advanced prostate cancer. From 12/15 to 4/16 I took cannabis oil and titrated my dose up to taking 325mg of both THC and CBD via rectal suppository daily. It made a slight dent in the rate of my PSA rise but didn't have the desired effect of curing me. So I tried the oil again from 1/17 to 5/17, this time doing a 2:1 ratio of CBD/THC and titrated up to 250mg CBD + 150mg THC taken orally (all I could tolerate.) It had no effect on the rate of the rise of my PSA. I obtained the oil from here (https://wamm.org/) and it was lab tested at SCLabs, so I was assured of the cannabinoid potency.

I always titrated up my oil dosing, and then titrated slowly off the oil for several weeks. I agree that the internet is full of snake oil salespeople and RSO dosing is a shotgun approach. One of the Nurse Practioners I know put together a 4 page file listing the best of recent cancer+cannibinoid research papers which I can share with you if you want.​

 

[Silat]

No disrespect taken ;-)

The reason I asked (in the THC break thread) is because I'm a retired RN and a member of the ACNA - American Cannabis Nurses Association - and am greatly interested in the evolving research on all things cannabis. You sound like an educated person and someone who has done quite a bit of research for yourself. The link you provided is good and you probably know that THC is an agonist at CB1 (in the central nervous system, primarily in the brain) and CB2 receptors (found distributed in the immune system the gut, spleen, liver, heart, kidneys, bones, blood vessels, lymph cells, endocrine glands and reproductive organs) while CBD is an antagonist. But how and why they affect cancer cells is still not clear. To say that CBD reverses or blocks the effect of THC at CB1 and CB2 receptors is true, but that doesn't explain the depressive features you observed.


Are you familiar with https://www.projectcbd.org/
or https://www.cannabisclinicians.org/directory/
Dr. Sulak's site is full of good information: https://healer.com/

FYI, I have advanced prostate cancer. From 12/15 to 4/16 I took cannabis oil and titrated my dose up to taking 325mg of both THC and CBD via rectal suppository daily. It made a slight dent in the rate of my PSA rise but didn't have the desired effect of curing me. So I tried the oil again from 1/17 to 5/17, this time doing a 2:1 ratio of CBD/THC and titrated up to 250mg CBD + 150mg THC taken orally (all I could tolerate.) It had no effect on the rate of the rise of my PSA. I obtained the oil from here (https://wamm.org/) and it was lab tested at SCLabs, so I was assured of the cannabinoid potency.

I always titrated up my oil dosing, and then titrated slowly off the oil for several weeks. I agree that the internet is full of snake oil salespeople and RSO dosing is a shotgun approach. One of the Nurse Practioners I know put together a 4 page file listing the best of recent cancer+cannibinoid research papers which I can share with you if you want.​

I am sorry about your battle with prostate cancer.

Please do share the NP's best of papers...

 

[MinnBobber]

One of the Nurse Practioners I know put together a 4 page file listing the best of recent cancer+cannibinoid research papers which I can share with you if you want.

I'd like to see that as the more info, the better.

Cancer fighting ratio:
I do a lot of research and one Calif Dr seen in many videos (can't place his name right now?) shared his thoughts from 15+ years of experience with treating 10,000? plus patients. Granted, each person reacts differently, there is no one size fits all.
His experience was that a THC : CBD ratio of 3:1 was the best for cancer patients.
Anecdotal, yes, but based on a large number of patients.

That's why we really need more research studies----hopefully they are happening???

 

[boocoodinkydow]

T

What are the favorite online shops for Terpenes?

True Terpenes/Buy Terpenes is my choice.

Several of my compadres and I formed a “research team”. Collectively we purchased samples of most all the strain mimicking formulas they had at that time and documented our results for a six month period. We tried to maintain an analytical approach to the project but often subjective overtones crept in. We tested the different formulas individually and didn’t divulge or opinions until we attended our weekly meetings to share results, hoping to avoid suggestive bias. We quickly found all terpenes are not created equally.

Our tests primarily involved treating ethanol extracted tincture. We used several strains as a base for the tincture but Blue Dream was the base most often used.

Overall, it seemed that the sativa dominate based Terpenes were more appealing than indicas. Super Lemon Haze was the collective fave with Green Crack and Durban Poison also offering satisfying results. Some of the indica mimicking strains were uncomfortable, inducing a depressive state for some.

As a group, we attempted to investigated the creation of custom formulations using their isolates. The almost infinite possibilities quickly became a labyrinth of confusion and was abandoned.

I have recently purchased their Essential Package containing five of the more prominent isolates. Initially, I was having only moderate success but the more I’m learning the more satisfying results I’m achieving.

Forgive the lack of brevity.

 

[C No Ego]

think of THC like chemo and the CBD as repair compound... THC can repair too but the agonist property of THC makes it more of an initial cleanser to eliminate directly ( via calcium transit) with agonist pressure. the antagonism of CBD then makes more enzymatic pressure on all of the cellular mechanisms that help to maintain the cell. basically, it has to do with how CBD directs more so to immune response

this thread seems to be all over the place chaos is a great thing

 

[C No Ego]

T


True Terpenes/Buy Terpenes is my choice.

Several of my compadres and I formed a “research team”. Collectively we purchased samples of most all the strain mimicking formulas they had at that time and documented our results for a six month period. We tried to maintain an analytical approach to the project but often subjective overtones crept in. We tested the different formulas individually and didn’t divulge or opinions until we attended our weekly meetings to share results, hoping to avoid suggestive bias. We quickly found all terpenes are not created equally.

Our tests primarily involved treating ethanol extracted tincture. We used several strains as a base for the tincture but Blue Dream was the base most often used.

Overall, it seemed that the sativa dominate based Terpenes were more appealing than indicas. Super Lemon Haze was the collective fave with Green Crack and Durban Poison also offering satisfying results. Some of the indica mimicking strains were uncomfortable, inducing a depressive state for some.

As a group, we attempted to investigated the creation of custom formulations using their isolates. The almost infinite possibilities quickly became a labyrinth of confusion and was abandoned.

I have recently purchased their Essential Package containing five of the more prominent isolates. Initially, I was having only moderate success but the more I’m learning the more satisfying results I’m achieving.

Forgive the lack of brevity.

are you using the terps alone or titrating your cannabis with them ?

 

[boocoodinkydow]

are you using the terps alone or titrating your cannabis with them ?

Our research team was adding terpenes to tincture primarily.

Presently, I’ve made several different formulations of the terpene isolates. Recently, I’ve been experimenting with full spectrum CBD with less than stellar results; primary objection being a lethargic overtone that was almost debilitating when trying to find motivation to carry on with even simple tasks.

I’m now using ethanol extracted tincture contains approximately 1mg of THC, 1 drop of various terpene formulations and about 25mg of full spectrum CBD with .3% THC.

Testing continues but I am definitely noticing the differential driving forces afforded by the the different terpene formulations.

FWIW, in the past, simple for the sake of “inquiring minds wanted to know” I mixed some terpene additives to pure MCT oil with no cannabis. To my surprise, it did offer a mild mind altering state.

 

[C No Ego]

Our research team was adding terpenes to tincture primarily.

Presently, I’ve made several different formulations of the terpene isolates. Recently, I’ve been experimenting with full spectrum CBD with less than stellar results; primary objection being a lethargic overtone that was almost debilitating when trying to find motivation to carry on with even simple tasks.

I’m now using ethanol extracted tincture contains approximately 1mg of THC, 1 drop of various terpene formulations and about 25mg of full spectrum CBD with .3% THC.

Testing continues but I am definitely noticing the differential driving forces afforded by the the different terpene formulations.

FWIW, in the past, simple for the sake of “inquiring minds wanted to know” I mixed some terpene additives to pure MCT oil with no cannabis. To my surprise, it did offer a mild mind altering state.

phytocannabinoids are terpenes too... they are monoterpenes... no smell, no volatility. bi- cyclic sesquiterpenes are the volatile terps... all terpenes become terpinoids when we metabolize them

https://www.bionity.com/en/encyclopedia/Terpene.html
https://www.bionity.com/en/encyclopedia/Terpenoid.html

 

[hans solo]

https://www.wikileaf.com/thestash/does-using-cbd-to-treat-your-anxiety-work/

Interesting

 

[Silat]

T


True Terpenes/Buy Terpenes is my choice.

Several of my compadres and I formed a “research team”. Collectively we purchased samples of most all the strain mimicking formulas they had at that time and documented our results for a six month period. We tried to maintain an analytical approach to the project but often subjective overtones crept in. We tested the different formulas individually and didn’t divulge or opinions until we attended our weekly meetings to share results, hoping to avoid suggestive bias. We quickly found all terpenes are not created equally.

Our tests primarily involved treating ethanol extracted tincture. We used several strains as a base for the tincture but Blue Dream was the base most often used.

Overall, it seemed that the sativa dominate based Terpenes were more appealing than indicas. Super Lemon Haze was the collective fave with Green Crack and Durban Poison also offering satisfying results. Some of the indica mimicking strains were uncomfortable, inducing a depressive state for some.

As a group, we attempted to investigated the creation of custom formulations using their isolates. The almost infinite possibilities quickly became a labyrinth of confusion and was abandoned.

I have recently purchased their Essential Package containing five of the more prominent isolates. Initially, I was having only moderate success but the more I’m learning the more satisfying results I’m achieving.

Forgive the lack of brevity.

Lack of brevity is perfect....
Thanks for the information..

 

[fernand]

Warmest sympathy and encouragement to anyone
who's suffering cancer. I hope nobody is foolhardy
enough to reject other treatment methods and only
use cannabis. There is cellular level evidence to suggest
that Chemotherapy and Cannabis can work better together
than either one alone.

I'm a research pharmacologist by training, though I've
spent more years as a design engineer. I'm afraid
we're all on our own at this point, for so many reasons.

Let me just throw out a thought, based on observation
and trying to stay on top of the research. Physiology is
tied into what we call emotion in ways we are just starting
to understand. The endocannabinoid system regulates
the biochemistry of the immune system, organ level
physiology, mood and and consciousness. We're still very
far from being able to pinpoint any of this at the receptor
level, and we shouldn't get sucked into facile explanations.

But another thread that's emerging is that perhaps the most
important vector of disease is that an inflammatory state,
that normally combats short term infection, goes out of
balance, becoming a constant state of stress, and attacking
our own bodies. For instance, atherosclerosis, that leads to
heart attacks and strokes, seems to result from inflammation
and a raised level of substances in the blood called CTRA,
more than, say, fats in the diet. A little known paper by
SW Cole tested the effect of different behaviors on the
CTRA level. He found that specifically acts of kindness
towards others lowered the CTRA. Other studies are now
examining the devastating effect of loneliness and despair
in raising the inflammatory markers in our blood, and the
immense benefits of positive emotion and group engagement
in improving outcomes. Old wives' tales come around.

Coming back to the CBD topic, at the cellular level there are
a few studies that attempt to identify which cannabinoids
are most active against which types of cancer cells, but this
is in its infancy. The shotgun use of a complete cannabis
extract is still the most plausible approach. To take a leap
with the above findings, it's plausible that THC:CBD ratios
that produce a positive outlook are more likely to be helpful
than those that do not. If you feel joy and express kindness
towards others, you're more likely to get well.

I believe that the current overemphasis on CBD, a trend
that is rooted in the old anti-cannabis prejudices, divisive
socio-political issues and powerful profit motives, is not very
helpful. Not that CBD is useless, far from it. It has some very
credible potential, but it seems least useful used by itself. The
degree to which it diminishes the joy response to THC is maybe
the best indicator and guide to dosage. If patients feel happier,
it's the right direction. If there's no effect on outlook, or if
the mood is gloomier, that's likely not to be helpful.

The reason to try including more CBD is theoretical. In day
to day effects it's the higher THC ratios that seem most helpful.

In the one colorectal cancer patient I'm most familiar with,
a THC:CBD ratio of 4:1 to 8:1, with daily oral + suppository
THC doses in the 500-700mg range has been well tolerated
and seems to be having greatest benefit in suppressing chemo
side effects, on outlook, on cancer markers, and on the size
and activity of the tumor(s) as seen in CAT and PET scans.

 

[3dfx-glide]

Wow, those are insane doses! 500-700mg THC? I'm an all day micro doser and I'm pretty toked after ~8mg THC! Not saying crazy high in the medical sense of course but just from a regular user perspective