That is a really subjective question. I am a heavy medical user, so my tolerances are different. I also medicate for different effects. Some effects I don't need to be as medicated, while others I need to medicate more. For example, anxiety requires light constant level of medicated. Pain reduction/relief requires a stronger level of medicated. So it is really subjective. Now that being said I will answer your question. One fully packed and loaded trench gets me where I need to be for minor Pain Relief. If I am feeling stressed and only need to calm down... maybe half a session. Hope that helps quantify it more.