Pain Management - how do you cope?

DRCousCous

New Member
I find getting as"high"as possible extremely therapeutic.
😩
There are definitely times I feel that way, but not at 7:30am when I have PT at 8:00am and a blood draw at... I usually have to delay heavy medication until later in the day.

But yeah, there are days when...I’m looking for the largest possible therapeutic dosage in the least amount of time. So far, the enail fits that niche pretty well for me
 
DRCousCous,
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shredder

Well-Known Member
For those suffering from pain/nausea/anxiety there is now evidence that cbda may be more effective than cbd.

cbda-vs-cbd-what-are-the-differences-312019

It all began in 2008, when researchers noticed that the molecular structure of CBDA closely resembled that of other common nonsteroidal anti-inflammatory drugs (NSAIDs). The team then investigated the potential of CBDA to act as an anti-inflammatory agent and found that CBDA demonstrated the same COX-2 inhibitor behavior that enables NSAIDs to tackle inflammation.

CBDA is also thought to be a powerful treatment for nausea and anxiety. A 2013 study from scientists in Guelph, Canada, found that CBDA was a thousand times more powerful than CBD in binding to a specific serotonin receptor linked to anti-nausea and anti-anxiety effects when administered alongside low-doses of the traditional anti-nausea drug for chemotherapy patients, ondansetron (OND).
 

DRCousCous

New Member
For those suffering from pain/nausea/anxiety there is now evidence that cbda may be more effective than cbd.

cbda-vs-cbd-what-are-the-differences-312019

It all began in 2008, when researchers noticed that the molecular structure of CBDA closely resembled that of other common nonsteroidal anti-inflammatory drugs (NSAIDs). The team then investigated the potential of CBDA to act as an anti-inflammatory agent and found that CBDA demonstrated the same COX-2 inhibitor behavior that enables NSAIDs to tackle inflammation.

CBDA is also thought to be a powerful treatment for nausea and anxiety. A 2013 study from scientists in Guelph, Canada, found that CBDA was a thousand times more powerful than CBD in binding to a specific serotonin receptor linked to anti-nausea and anti-anxiety effects when administered alongside low-doses of the traditional anti-nausea drug for chemotherapy patients, ondansetron (OND).
I’ll look into the CBDa. It is super cheap and easy to get online, and I could use that in addition to the other cannabinoids!
I personally really despise Ondansetron. I have extreme nausea, loss of appetite, etc. (similar to what happens with chemo patients), and OND is...the worst. Sure, it will stop me puking in the middle of the night, but it completely stops my digestive system.

No puke, no poop, no digestion, no nothing...gets very uncomfortable after a while. In short, I’m always up for new ways to shortcut nausea.
 
I’ve been lurking and following this thread a while. I want to try to answer the thread topic question, as an introduction of sorts.

I have a very, very rare disease called Moersch-Woltmann Syndrome or “Stiff Person Syndrome.” It is a progressive, incurable neuromuscular disorder, and not much is really known about it. Probably autoimmune, definitely debilitating, and difficult to treat.

The primary feature of SPS is a failure in the GABA system, so certain muscle groups literally can’t “turn off.” Untreated, I have muscle spasms 24 hours a day in my trunk and upper parts of my legs. Worse spasms can break bones and tear ligaments. It sucks!

I am treated with Immune Globulin, very high doses of Baclofen, Diazepam, and Duloxetine. These mostly control the bad spasms. But, they are all CNS depressants, so I can’t take opioids for pain (until it is give up and hospice time, which ain’t yet for me). Three different doctors told me “go look into CBD and THC for pain and spasticity relief.”

I hadn’t used marijuana in 25 years at that point, and let me tell you...things have changed! Took me a while to figure out what works for me (and it changes):

* I make and eat 1:1 CBD:THC edibles (glycerine or fat/lecithin) through the day as a base layer

* I vape 1:1:1 CBG:CBD:THC dry herb starting in the mornings when I don’t have to be out for an appointment (in which case it’s CBG:CBD).

* I vape more and more THC as the day progresses, usually to the point of ending the day with just THC herb.

* I use “session” vapes several times a day (DiTanium and SBL Runt); I microdose frequently with a DynaVap.

* I occasionally use concentrates as either bowl toppers or with an enail (DiTanium) if I’m in a ton of pain.

Does any of it work? Not really, at a deep level. But it helps enormously for me and n a few fronts which affect my chronic pain: it helps me to get and stay relaxed, physically and mentally, which reduces pain for me; it helps to buffer a symptom of SPS I have called “ekplexia” which causes extreme startle responses (and falls, injuries, etc.); and it allows me to focus on things other than pain.

I’ve gravitated towards heavy “indica” types and away from strains people describe as “energizing” or “creative.” Make me anxious. I love the purples and kushes and GSC phenos. They work, and they taste good too.

What I need help with (only six months in) is how to protect my throat and lungs as much as possible. I’ve started vaping through water, which helps some. But...I vape a lot, and edibles don’t seem to really do it for me. How do you all cope with throat and lung irritation?
@DRCousCous, I was also very concerned about throat and lung irritation as my throat is super sensitive. I was a recreational user back in the late 70s but quit using when I was raising my children. After several surgeries (back, neck & knee), osteoarthritis and fibromyalgia brought chronic pain into my life I decided to get my card. I started with the pre-filled carts but didn't like the taste and more important the uncertainty of what I was inhaling. I found that my lungs hurt after vaping even though it didn't irritate my throat. Scary. Plus they gave me headaches. I started researching flower vapes with my hunt focused on a device that would not be harsh on my throat. I decided on the Tafee Bowle for my 1st dry herb vape and am really pleased with it. No lung or throat irritation AT ALL, and no more headaches. As a matter of fact, the vapor feels cool going in. It is SUPER easy to draw from, unrestricted which is usually not the case I've heard about pure convection vapes. There is a thread on it. People are raving about it. Again, it's my 1st dry herb vape so I can't compare it to anything but I absolutely would not feel the need to use it through water.
 

DRCousCous

New Member
For those suffering from pain/nausea/anxiety there is now evidence that cbda may be more effective than cbd.

cbda-vs-cbd-what-are-the-differences-312019

It all began in 2008, when researchers noticed that the molecular structure of CBDA closely resembled that of other common nonsteroidal anti-inflammatory drugs (NSAIDs). The team then investigated the potential of CBDA to act as an anti-inflammatory agent and found that CBDA demonstrated the same COX-2 inhibitor behavior that enables NSAIDs to tackle inflammation.

CBDA is also thought to be a powerful treatment for nausea and anxiety. A 2013 study from scientists in Guelph, Canada, found that CBDA was a thousand times more powerful than CBD in binding to a specific serotonin receptor linked to anti-nausea and anti-anxiety effects when administered alongside low-doses of the traditional anti-nausea drug for chemotherapy patients, ondansetron (OND).
So, I’ve been thinking about this, partially because high CBDa hemp is very inexpensive at the moment and easily available. Can you do a normal low temperature extraction to capture CBDa in a useable form? Seems a glycerine tincture without decarbing could work, or getting a CBDa concentrate and dispersing in oil?

Are CBDa products available or recommend by folks here?
 
DRCousCous,
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DRCousCous

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@DRCousCous, I was also very concerned about throat and lung irritation as my throat is super sensitive. I was a recreational user back in the late 70s but quit using when I was raising my children. After several surgeries (back, neck & knee), osteoarthritis and fibromyalgia brought chronic pain into my life I decided to get my card. I started with the pre-filled carts but didn't like the taste and more important the uncertainty of what I was inhaling. I found that my lungs hurt after vaping even though it didn't irritate my throat. Scary. Plus they gave me headaches. I started researching flower vapes with my hunt focused on a device that would not be harsh on my throat. I decided on the Tafee Bowle for my 1st dry herb vape and am really pleased with it. No lung or throat irritation AT ALL, and no more headaches. As a matter of fact, the vapor feels cool going in. It is SUPER easy to draw from, unrestricted which is usually not the case I've heard about pure convection vapes. There is a thread on it. People are raving about it. Again, it's my 1st dry herb vape so I can't compare it to anything but I absolutely would not feel the need to use it through water.
Thank you for the recommendation! I have a similar (in some ways) desktop vape, but that does look like an interesting portable option. I really like pure convection, and low temps are really important (for me). Cheers!
 
DRCousCous,

shredder

Well-Known Member
So, I’ve been thinking about this, partially because high CBDa hemp is very inexpensive at the moment and easily available. Can you do a normal low temperature extraction to capture CBDa in a useable form? Seems a glycerine tincture without decarbing could work, or getting a CBDa concentrate and dispersing in oil?

Are CBDa products available or recommend by folks here?

I grow cannatonic #4. It's a high cbd, low thc plant. After harvest I make almost all of it into rosin. And I use the rosin along with thc concentrates in our medibles. I have never tested the rosin itself but I suspect there is at least some cbda in it. I press at 190F, but under a lot of pressure.

If I were to extract just for cbda, a low temperature, long time infusion seems best, something like a sous vide infusion, or using cold alcohol.

I stay away from trying to extract with glycerine, it just is not efficient at all. Been there, done that. Oils or alcohol are much better at extracting.

Ive never bought any cbd product, so I can't give any advice commercial products.
 

DRCousCous

New Member
I grow cannatonic #4. It's a high cbd, low thc plant. After harvest I make almost all of it into rosin. And I use the rosin along with thc concentrates in our medibles. I have never tested the rosin itself but I suspect there is at least some cbda in it. I press at 190F, but under a lot of pressure.

If I were to extract just for cbda, a low temperature, long time infusion seems best, something like a sous vide infusion, or using cold alcohol.

I stay away from trying to extract with glycerine, it just is not efficient at all. Been there, done that. Oils or alcohol are much better at extracting.

Ive never bought any cbd product, so I can't give any advice commercial products.
I don’t buy anything but CBD bud myself. Don’t trust most and can’t afford dispensary bud. And I’m not currently in a position to grow my own, unfortunately.

I am not a fan of glycerine either. You can get very potent tinctures, but it requires months and a lot of stirring and babying and re-steeping and...

I mostly use coconut oil these days, plenty of saturated fats to grab the beneficials. And I’m pretty sure you could use a low temp bath (sous vide) to melt the coco and get near full extraction. I’ve also been considering lab heat plates with magnetic stirrers. Cheaper (and maybe more efficient) than a sous vide. I avoid ethanol due to recovering alcoholics in the household.

I have an ounce of some OK hemp bud I wouldn’t mind using up, so I might give it a shot and report back. Have you ever done testing?

also, and I swear it is the last q... where do your get your seeds, and do you grow clones, autos, fems, or from seed for breeding?
 

kapows

New Member
I grow cannatonic #4. It's a high cbd, low thc plant. After harvest I make almost all of it into rosin. And I use the rosin along with thc concentrates in our medibles. I have never tested the rosin itself but I suspect there is at least some cbda in it. I press at 190F, but under a lot of pressure.

If I were to extract just for cbda, a low temperature, long time infusion seems best, something like a sous vide infusion, or using cold alcohol.

I stay away from trying to extract with glycerine, it just is not efficient at all. Been there, done that. Oils or alcohol are much better at extracting.

Ive never bought any cbd product, so I can't give any advice commercial products.

you in the uk? :D
 
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shredder

Well-Known Member
I mostly use coconut oil these days, plenty of saturated fats to grab the beneficials. And I’m pretty sure you could use a low temp bath (sous vide) to melt the coco and get near full extraction. I’ve also been considering lab heat plates with magnetic stirrers. Cheaper (and maybe more efficient) than a sous vide. I avoid ethanol due to recovering alcoholics in the household.

I have an ounce of some OK hemp bud I wouldn’t mind using up, so I might give it a shot and report back. Have you ever done testing?

also, and I swear it is the last q... where do your get your seeds, and do you grow clones, autos, fems, or from seed for breeding?

You might want to look into mct oil as well. It stays liquid at room temps and is pretty neutral tasting. I made a strong infusion with mct and feco. I can actually feel the effects in 15 minutes if I put a few drops in my morning coffee.

I've never worked with hemp, just one cbd plant, cannatonic #4. The buds tested at 15% cbd and .5% thc.
I got the cutting that started my grow from another grower at our local compassion club. It has since disbanded after my state became legal. Most of my other plants came from a small circle of friends that grow and occasionally I'll purchase seeds online. If I like a plant I take cuttings from it to grow more of that variety. Ive grown cannatonic for 7 years running. And I share with other growers that need cuttings.
you in the uk? :D
Nope, I live in Michigan, USA.

My state has been legal several years now.
 

cvs8floz

Well-Known Member
@shredder thats awsome, i used to have that plant around few years back and was making rosin from it aswell, the edibles i made from that rosin had some serious medical value, i also dabbed the rosin and the terps was crazy, Juanita la Lagrimosa
This strain is sold by Elite Seeds out of Spain, I just finished growing one of their La Rica auto seeds, advertised as 1:1 CBD/THC. I am getting more and more into the 1:1 strains, they used to be my base followed by something heavier to cap the night, I now find that they get me pleasantly high, sometimes even more high than the heavy hitters. Pyramid Seeds Northern Lights CBD and Sensi #743 are other good ones, the latter is adverised as 2:1 THC/CBD and has an amazing scent.
 
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