This happens a lot in the “science” community - they use the word “cannabis” but if you jump into the study it tells a different story.
Right off the bat we see a slew of highly purified, fractionated, isolated and synthetic cannabinoids and patent medicine. Where’s the cannabis at?
One of the endothelial studies asserts that CBD is inflammatory but what about the MCT oil it’s diluted with? There’s a reason everybody quit doing that...
Not a huge fan of these “meta analyses” in general - often seems very correlative and frankly unscientific. This is all assuming the study participants are relatively healthy to begin with to even attempt to demonstrate a pattern. But the actual chances of that are fairly slim as well which makes the science even more theoretical, rather than demonstrable.
So yeah, I wouldn’t expect too much pain relief from fragmented synthetic research chemicals.
Even if they used real cannabis, what are the chances that “one size fits all?”
I bet you’d get pain relief if you had access to real sun grown, seed grown, Afghan Kush. White Runtz from clone grown in a sterilized and climate controlled grow room on the other hand? Eh...
Unfortunately the scientific community doesn’t generally mesh well with metaphysics and natural law so this side of thinking is often omitted from the discussion. Obviously whole plant medicine presents a monetization issue for the pharmaceutical conglomerates who fund most of this type of research.
Also the idea that the endothelial inflammation is caused by THC and not the irritants present from the hot smoke inhalation seems pretty silly. I call this the “microscope effect” - it’s when someone is zoomed in so closely on a subject that they can’t even see what they are looking at any more. When you zoom out you see plenty of more plausible scenarios. Prior research has shown THC to be 20x more powerful than aspirin for inflammation.
Also anecdotally when my mom was going through cancer I found peppermint essential oil to work much better for nausea than cannabis. It’s pretty simple really, it’s very difficult to ingest cannabis orally when you’re already nauseous and vomiting. Essential oils applied topically absorb nearly instantly into the bloodstream, or you can diffuse them which is a little slower administration but still very effective. The organic steam distilled peppermint oil was absolutely incredible for nausea. Most likely the essential oil components in cannabis are some of the most powerful components as well, but most aren’t consuming in a way that would preserve these optimally.
www.analyticalcannabis.com
med.stanford.edu
