From the dosing guide I followed, "extremely high" is synonymous with "macrodose".
The risks of using increase with dosage, and they include: drowsiness, dizziness, dry mouth, anxiety, nausea, cognitive effects, euphoria, blurred vision, headache, orthostatic hypertension, psychosis, depression, ataxia, tachycardia, hyperemesis and diarrhoea. Such side effects are only possibilities, with many of them minor and others quite rare.
Medical guidelines aim for greatest benefit with least risk, and with little therapeutic benefit from THC dosage exceeding 40 mg/day higher doses are generally not recommended. Risks such as tachycardia and psychosis make THC potentially dangerous for some users, and it is also not recommended for pregnant women (mainly because its effects on an unborn child are uncertain).
Tolerance to THC will increase without regular breaks of two days or more, but its therapeutic effects do not diminish, and patients requiring higher doses generally have a high pre-existing tolerance or they are overusing their medicine for non-medical purposes.
Recreational users will adjust their usage to avoid discomfort, and if side effects are not experienced there is no practical limit to consumption. The main problem is increasing tolerance leading to greater use, with an increased risk of dependency and withdrawal symptoms on cessation.
The degrees of dosage previously described were based on medical considerations, and non-medical users perhaps need a different scale. For habitual macrodosers using without medical guidance the only defined limit is the (ridiculously high) level required for toxicity, with high or low doses determined mainly by one's own situation. While medical use can (to some extent) be objectively assessed, recreational use remains subjective.
The risks of using increase with dosage, and they include: drowsiness, dizziness, dry mouth, anxiety, nausea, cognitive effects, euphoria, blurred vision, headache, orthostatic hypertension, psychosis, depression, ataxia, tachycardia, hyperemesis and diarrhoea. Such side effects are only possibilities, with many of them minor and others quite rare.
Medical guidelines aim for greatest benefit with least risk, and with little therapeutic benefit from THC dosage exceeding 40 mg/day higher doses are generally not recommended. Risks such as tachycardia and psychosis make THC potentially dangerous for some users, and it is also not recommended for pregnant women (mainly because its effects on an unborn child are uncertain).
Tolerance to THC will increase without regular breaks of two days or more, but its therapeutic effects do not diminish, and patients requiring higher doses generally have a high pre-existing tolerance or they are overusing their medicine for non-medical purposes.
Recreational users will adjust their usage to avoid discomfort, and if side effects are not experienced there is no practical limit to consumption. The main problem is increasing tolerance leading to greater use, with an increased risk of dependency and withdrawal symptoms on cessation.
The degrees of dosage previously described were based on medical considerations, and non-medical users perhaps need a different scale. For habitual macrodosers using without medical guidance the only defined limit is the (ridiculously high) level required for toxicity, with high or low doses determined mainly by one's own situation. While medical use can (to some extent) be objectively assessed, recreational use remains subjective.
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