Robert Hooke, one of the greatest scientists ever, on cannabis, which i had frankly forgotten about til last night's Cosmos, though I was obsessed with the dude in grad school:
This Powder being chewed and swallowed, or washed down, by a small Cup of Water, doth, in a short Time, quite take away the Memory and Understanding; so that the Patient understands not, nor remembereth any Thing that he seeth, heareth, or doth, in that Extasie, but becomes, as it were, a mere Natural, being unable to speak a Word of Sense; yet is he very merry, and laughs, and sings, and speaks Words without Coherence, not knowing what he saith or doth; yet is he not giddy, or drunk, but walks and dances and sheweth many odd Tricks; after a little Time he falls asleep, and sleepeth very soundly and quietly; and when he wakes he finds himself mightily refresh’d, and exceeding hungry. And that which troubled his Stomach, or Head, before he took it, is perfectly carried off without leaving any ill Symptom, as Giddiness, Pain in the Head or Stomach, or Defect of Memory of any Thing (besides of what happened) during the Time of its Operation.
[Hooke's friend and collaborator, Knox] has so often experimented it himself, that there is no Cause of Fear, tho' possibly there may be of Laughter