Cannabinoid hyperemesis syndrome

[C No Ego]

Gotcha. I've just been seeing it all over the local news lately and was just worried it was becoming rampant as all the articles seem to think it's becoming a major problem

yeah, just focus on using amounts that help you ... do not just keep inhaling active lipophilic cannabis compounds all day long for a high... your response to satiety is modulated ( munchies)... this tells you to turn on hunger or turn it off... toggling that Leptin/ grehlin response can make it not work as well over time hence some people start to upchuck. Extreme Munchie signals

 

[wormraper]

LOL. I'm definitely not an all-day toker. I tend to get good and high about two to three times a week at most for a few hours each session and just sit and get baked in front of the TV. I don't sit and wake and bake all day

 

[invertedisdead]

LOL. I'm definitely not an all-day toker. I tend to get good and high about two to three times a week at most for a few hours each session and just sit and get baked in front of the TV. I don't sit and wake and bake all day

You're fine

 

[Tranquility]

https://cannabislifenetwork.com/solving-cannabis-hyperemesis-syndrome/

...
The idea that CHS is caused by the activation of this noxious pain signaling channel is further supported by its treatments. While TRPV1 answers this fairly conclusively, the other remedy is a dopamine inhibitor. Neurological responses to your immune system and environmental conditions occur through TRP channels, which are strengthened by ACH, a molecule that compensates dopamine. Pinene will help prevent ACH’s degradation which means it will make CHS worse. Caryophyllene, on the other hand, is known to inhibit dopamine by activating the CB2 receptor, so it is likely caryophyllene will help relieve CHS symptoms. Aside from dopamine inhibition, CHS is a condition that causes THC to pit the neurological system against the immune system, turning the body into an internal warzone that can only be extinguished by fire.

Some have kept themselves in a shower so hot for so long they became dehydrated and worse. There are reports of failed kidneys due to the intensity of the hot water. Abstinence to cannabis is a must, but caryophyllene may help, if it does not make it worse that is. We will explain how legal weed may be supporting evidence for caryophyllene’s benefit, and take a deeper dive into dopamine’s relationship with CHS.​

 

[Tranquility]

But wait, there's more!
https://cannabislifenetwork.com/how-legal-cannabis-relieves-chs-limits-of-irradiation/

...
Well, call it what you want considering CHS has no real cause and effect truly defined for it. Nothing yet proves it as anything more than cyclic vomiting syndrome, unrelated to a person’s cannabis use history. We analyzed a theory to explain the mystery, one that involves abnormal signalling in a cannabinoid receptor. Preclinical analysis suggests that a shift in the receptor’s response to biased agonists, like THC can potentially cause pain and nausea with certain genetic presets. If that is true, then switching from an untested grey market to legal cannabis might have actually stopped their symptoms! ...​

 

[newVaper420]

But wait, there's more!
https://cannabislifenetwork.com/how-legal-cannabis-relieves-chs-limits-of-irradiation/

...
Well, call it what you want considering CHS has no real cause and effect truly defined for it. Nothing yet proves it as anything more than cyclic vomiting syndrome, unrelated to a person’s cannabis use history. We analyzed a theory to explain the mystery, one that involves abnormal signalling in a cannabinoid receptor. Preclinical analysis suggests that a shift in the receptor’s response to biased agonists, like THC can potentially cause pain and nausea with certain genetic presets. If that is true, then switching from an untested grey market to legal cannabis might have actually stopped their symptoms! ...​

Not true. I was driving up to Rhode Island to the legal medical dispensary and I got way sicker.

I’ve stopped using for 5 months and i have no issues. Previously i was sick everyday and had 7 episodes with 4 in the ER.

I’m jealous of the people who don’t have CHS, but if you do have it, the only way to fix it is to stop using cannabis all together.

 

[Truth Seeker]

Not true. I was driving up to Rhode Island to the legal medical dispensary and I got way sicker.

I’ve stopped using for 5 months and i have no issues. Previously i was sick everyday and had 7 episodes with 4 in the ER.

I’m jealous of the people who don’t have CHS, but if you do have it, the only way to fix it is to stop using cannabis all together.

Sorry to hear about your CHS, glad you did what you have to do to solve it!
Were you primarily vaping flower or concentrates prior to your Diagnosis?
It seems like it's all across the board with a wide age range and such and it seems like concentrates especially vape pens/carts really have been in use by a lot of young people prior to Diagnosis yet a lot of older stoners are starting to get it too and they are mostly flower smokers......It's a crazy thing and scary for those that have gone through it. Glad your well!

 

[chris 71]

Not true. I was driving up to Rhode Island to the legal medical dispensary and I got way sicker

I wouldnt have thought you guys down in the states would even have irradiated cannabis ?

Not sure what to make of the articale that oldNewbie posted , seem like therioes all over the place with the CHS stuff maybe with it being more regulated up here in canada we will get more real answers someday soon

 

[newVaper420]

Sorry to hear about your CHS, glad you did what you have to do to solve it!
Were you primarily vaping flower or concentrates prior to your Diagnosis?
It seems like it's all across the board with a wide age range and such and it seems like concentrates especially vape pens/carts really have been in use by a lot of young people prior to Diagnosis yet a lot of older stoners are starting to get it too and they are mostly flower smokers......It's a crazy thing and scary for those that have gone through it. Glad your well!

I was sick way before concentrates and vape pens were even a thing. I got sick around 2001/2002. First memorable episode was in 2006. I only started vape carts and dabbing lets say in the past 3 years. Dabbing made it way way worse.

Anyhow, still jealous of everyone able to consume, but I can’t anymore. I really need to sell my vape equipment.

 

[rnartian]

Whoooa. Just read up on this and holy shit, could this be why I get so nauseous when I smoke herb?? I know people use it for nausea, but I've always gotten a sick feeling when I smoke or vape, and have to wait for it to pass.

It MIGHT be a type of terpene that causes it. I just avoid certain types of cannabis now, that have smells I associate with stomach pain or feeling sick.

 

[Victarion]

Whoooa. Just read up on this and holy shit, could this be why I get so nauseous when I smoke herb?? I know people use it for nausea, but I've always gotten a sick feeling when I smoke or vape, and have to wait for it to pass.

It MIGHT be a type of terpene that causes it. I just avoid certain types of cannabis now, that have smells I associate with stomach pain or feeling sick.

I am curious, which kind of small do you associate with these symptoms?

 

[rnartian]

I am curious, which kind of small do you associate with these symptoms?

Stuff that has kind of a woodsy smell. I also notice it with things that have a peppery smell, but those are the strains that help the most with anxiety for me, so I just try and wait for it to pass. Idk an example of the woodsy smell, since I didn't know it's strain, but Girl Scout Cookies is one of the ones with a peppery/spicy kind of smell to me. But, to be fair, it happens often with plenty of strains. I figured it was just part of smoking/vaping up to this point.

 

[newVaper420]

Stuff that has kind of a woodsy smell. I also notice it with things that have a peppery smell, but those are the strains that help the most with anxiety for me, so I just try and wait for it to pass. Idk an example of the woodsy smell, since I didn't know it's strain, but Girl Scout Cookies is one of the ones with a peppery/spicy kind of smell to me. But, to be fair, it happens often with plenty of strains. I figured it was just part of smoking/vaping up to this point.

Honestly, I'm not one to tell you what to do. You can see that I have a huge post count on this site, and was an avid fan of cannabis. But if it is CHS, you are better off avoiding all types of cannabis. My life is completely different since I stopped. No, this is not a coming to Jesus tale. I still love fucking weed. I miss it. I'm not gonna lie. But it was making me sick. It was toxic to me. I had a good 20 years of smoking every day all day. If you have any questions at all, don't hesitate to ask. I'm about 7 months out now.

People may say, why do you visit this site still. One, I have some vapes I need to sell, but I just haven't gotten around to it yet. Two, I get notifications in my email. LOL.

Anyhow, good luck on your journey, and hope you feel better, however you do it.

 

[shredder]

Stuff that has kind of a woodsy smell. I also notice it with things that have a peppery smell, but those are the strains that help the most with anxiety for me, so I just try and wait for it to pass. Idk an example of the woodsy smell, since I didn't know it's strain, but Girl Scout Cookies is one of the ones with a peppery/spicy kind of smell to me. But, to be fair, it happens often with plenty of strains. I figured it was just part of smoking/vaping up to this point.

You might want to try Columbian Gold or blue dream. Both are good for anxiety and neither have peppery terpenes.

 

[rnartian]

You might want to try Columbian Gold or blue dream. Both are good for anxiety and neither have peppery terpenes.

Thank you! I've never tried those, so I'll check them out next time.
I've only tried maybe 12 different strains, so I know there have to be strains that are safe. I'm glad to know this has a name, though, and I hope the rest of us can figure it out. Until then, I guess I'll experiment and hopefully find something that relieves my symptoms without making me feel sick.

 

[C No Ego]

Thank you! I've never tried those, so I'll check them out next time.
I've only tried maybe 12 different strains, so I know there have to be strains that are safe. I'm glad to know this has a name, though, and I hope the rest of us can figure it out. Until then, I guess I'll experiment and hopefully find something that relieves my symptoms without making me feel sick.

the Neem oil pesticide Azadirachin can cause the throw up feeling in some people , and it is considered organic pest control and used on many cannabis plants... if you are getting from the same source different strains it may not matter if all grown from the same grower using the same pesticide throughout

 

[newVaper420]

the Neem oil pesticide Azadirachin can cause the throw up feeling in some people , and it is considered organic pest control and used on many cannabis plants... if you are getting from the same source different strains it may not matter if all grown from the same grower using the same pesticide throughout

I wouldn't put too much faith into this reasoning. You need a lot A LOT of that pesticide to cause symptoms. There have been plenty of people who grow their own without using any pesticides and still throw up.

Anyhow, I encourage anyone who is getting sick from cannabis to really consider stopping for a little bit and see how they feel. And for a little bit, I mean 90 days. I didn't want to believe it myself, but it is real. And there are even people who wind up with much worse symptoms if they continue, and even death. Yes, I know most of you don't want to hear that here, trust me I didn't.

My last episode was in May. 13 hours of non-stop vomiting. Couldn't even drink a sip of water. Which eventually leads to dehydration, then kidney failure then death.

I just want people to realize, that there are lots of excuses for CHS, including this Neem Pesticide shit, but sometimes, we overload our bodies, or we just can't handle it anymore, and instead of cannabis being beneficial to us, it becomes toxic.

I'm not posting this to scare anyone, or to be like "you must do this", I just don't want people to suffer for 20 years of being sick like I was. It all comes from a good place. I still want marijuana to be legal. I still hang out with people who smoke/vape, and still hang around them when they smoke/vape. In fact, a bunch of my family still smoke, etc. I'm all for it.

I just don't want people to be sick, and thinking oh it can't be cannabis. Because I was in denial for a LONG LONG time.

 

[shredder]

@newVaper420 do you have the same effects from medibles?

I'm thinking less terpenes in medibles.

@rnartian I have a slight allergy to peppery, earthy terpenes. It makes my asthma act up if I have a lot of exposure. But I do fine with the citrusy lime/lemon or fruity terpenes.

 

[newVaper420]

@newVaper420 do you have the same effects from medibles?

I'm thinking less terpenes in medibles.

That's the fucked up part about it. It's not the terpenes. It's the cannabinoids. All of them. So even CBD can cause an hyperemesis episode. And in the beginning, while I was getting clean, I had to avoid foods that contain cannabinoids as well, black pepper, chocolate, everything. It was fucked. I've been sick since for like I said about 20 years. So before all this new age shit started, and before vaping was really a thing. I've had plenty of edibles they never really relieved my stomach symptoms and I wouldn't get high of them either. I would have to do an insane quantity to feel it. Towards the end of my run, I was driving to medical dispensaries up in Rhode Island, and getting high quality concentrates, and high quality bud. In fact, one time I was even invited into a legal medical marijuana growing operation in Rhode Island. It was incredible. I miss it so much, but I eventually had to come to the realization that I could not use ever again, because at any time, I could get thrown into an episode. And trust me when I tell you, I've been to the ER at least 4 times, with each stint winding me up in the hospital for 4 days. My last episode in May, bro, I really wanted to die. It was fucking awful. So I had to do what's best for me.

I really like this article: https://www.leafly.com/news/health/neem-oil-cannabinoid-hyperemesis-syndrome

 

[invertedisdead]

@newVaper420 does it come on randomly or is it automatic as soon as you start partaking again?

I got a buddy that has had at least a half dozen episodes of week long violent vomiting. The last one which happened recently caused him to get deathly dehydrated, doc put him on a saline drip which finally brought his hydration back under control.

I've mentioned CHS as a plausibility to him but with ~50 years of heavy usage it's hard to get the point across.

 

[C No Ego]

I wouldn't put too much faith into this reasoning. You need a lot A LOT of that pesticide to cause symptoms. There have been plenty of people who grow their own without using any pesticides and still throw up.

Anyhow, I encourage anyone who is getting sick from cannabis to really consider stopping for a little bit and see how they feel. And for a little bit, I mean 90 days. I didn't want to believe it myself, but it is real. And there are even people who wind up with much worse symptoms if they continue, and even death. Yes, I know most of you don't want to hear that here, trust me I didn't.

My last episode was in May. 13 hours of non-stop vomiting. Couldn't even drink a sip of water. Which eventually leads to dehydration, then kidney failure then death.

I just want people to realize, that there are lots of excuses for CHS, including this Neem Pesticide shit, but sometimes, we overload our bodies, or we just can't handle it anymore, and instead of cannabis being beneficial to us, it becomes toxic.

I'm not posting this to scare anyone, or to be like "you must do this", I just don't want people to suffer for 20 years of being sick like I was. It all comes from a good place. I still want marijuana to be legal. I still hang out with people who smoke/vape, and still hang around them when they smoke/vape. In fact, a bunch of my family still smoke, etc. I'm all for it.

I just don't want people to be sick, and thinking oh it can't be cannabis. Because I was in denial for a LONG LONG time.

I actually look to the Growers... they are front line and producing what everyone is ingesting... when seeing growers mention CHS type symptoms immediately after ingesting Neem oil cannabis , not after 50 years of use it is apparent... the main poster in that thread I mention gets CHS symptoms immediately after consuming dispensary weed and not his own grown weed with no neem on it...
and this is not to discredit your situation @ all and that just sucks , just showing what tghe findings are showing so far since CHS is not an issue for so many but a few

 

[newVaper420]

@newVaper420 does it come on randomly or is it automatic as soon as you start partaking again?

I got a buddy that has had at least a half dozen episodes of week long violent vomiting. The last one which happened recently caused him to get deathly dehydrated, doc put him on a saline drip which finally brought his hydration back under control.

I've mentioned CHS as a plausibility to him but with ~50 years of heavy usage it's hard to get the point across.

Nah, it's very sporadic. I'd be fine for 6 months to a year, then have an episode. But I would have continous abdominal pain everyday. That was the main reason I smoked, and went to the doctors for 20 years. Once I stopped smoking completely, no more pain. I've been completely normal.

I actually look to the Growers... they are front line and producing what everyone is ingesting... when seeing growers mention CHS type symptoms immediately after ingesting Neem oil cannabis , not after 50 years of use it is apparent... the main poster in that thread I mention gets CHS symptoms immediately after consuming dispensary weed and not his own grown weed with no neem on it...
and this is not to discredit your situation @ all and that just sucks , just showing what tghe findings are showing so far since CHS is not an issue for so many but a few

Check out that article I posted above. It's pretty good. Also, who knows what was on the weed I was smoking, but I've been smoking for 20 years, long before dispensaries existed, and I've been sick for a long long long time.

 

[C No Ego]

Nah, it's very sporadic. I'd be fine for 6 months to a year, then have an episode. But I would have continous abdominal pain everyday. That was the main reason I smoked, and went to the doctors for 20 years. Once I stopped smoking completely, no more pain. I've been completely normal.



Check out that article I posted above. It's pretty good. Also, who knows what was on the weed I was smoking, but I've been smoking for 20 years, long before dispensaries existed, and I've been sick for a long long long time.

there is a Term called - Bi-phasic , where the healthy properties in there actually reverse ... it is a type of up regulation... do you8 have issues eating to much omega fats ? are the CHS symptoms activated from those @ all in you? thanks, again, that completely sucks man

 

[newVaper420]

there is a Term called - Bi-phasic , where the healthy properties in there actually reverse ... it is a type of up regulation... do you8 have issues eating to much omega fats ? are the CHS symptoms activated from those @ all in you? thanks, again, that completely sucks man

Nope, nope and nope. Once I stopped smoking, I've been able to eat everything I was eating, and I haven't been sick at all. I'm about 7 months out, and been able to eat all sorts of shit that would otherwise make me all fucked up while I was smoking. Trust me, as much as I didn't want to believe it was the cannabis, it definitely was. I tried everything. NYS Medical Marijuana which were vape pens mixed with MCT, Rhode Island Medical Dispensary, California, fuck man, I even had an episode when I was in Amsterdam on my honeymoon. I would blame the food in Amsterdam, but looking back, had to be the weed. Like I said, 20 years of being sick, colonoscopies, all sorts of tests, everything always came back normal. Now, 7 months out, I feel better than I have ever felt. It sucks, because I loved smoking/vaping. Look at my post count. I was a huge huge proponent. Loved my Cloud Evo (In fact I have two). Grasshopper was amazing. E-Nano, Mighty, etc. I was big in. But I just can't be sick anymore.

And no matter what, I can't even take the chance. I've read plenty plenty plenty of stories of people who have grown their own without pesticides, and still got sick. Just not worth it for me.

Edit: Also, towards the end, I switched to concentrates to try to get better relief, and almost had two episodes back to back in a week. Man, I fucking loved those dabs and the puffco peak. I got fucking all types of concentrates too. 710labs, fresh press from a local guy. It was all fucking dope. :-(

 

[shredder]

I actually look to the Growers... they are front line and producing what everyone is ingesting... when seeing growers mention CHS type symptoms immediately after ingesting Neem oil cannabis , not after 50 years of use it is apparent... the main poster in that thread I mention gets CHS symptoms immediately after consuming dispensary weed and not his own grown weed with no neem on it...
and this is not to discredit your situation @ all and that just sucks , just showing what tghe findings are showing so far since CHS is not an issue for so many but a few

Neem oil is used in toothpaste and cosmetics so ingesting orally its safe. Inhaling? Who knows? Its an oil, so probably not good.

No growers I know of would spray neem oil on buds. Its used on vegging plants as an organic mite spray. But not once flowering starts. The taste would be a giveaway, it's unusual and distinctive.

I've read the concerns, but have not found a direct link, and I doubt there is a link.