What chemicals cause the uniqueness of each strain?

[Nosferatu]

Is it just the ratio of THC to the CBNs/CBDs/etc..? Or are there cannabinoids or something else that are unique to each strain, therefore causing the different effects?

Does anyone else think its harder to feel the difference of strains in a vape, versus smoking. It seems like smoking brings out the unique properties of the strain a little more than vaping does. But I'm not complaining, I still like vaping more, it just made me wonder if the unique high to each strain is more something in the plant matter itself.

 

[momatik]

I thought it was a combination of the 2.

I was under the impression that there are 50-some cannabinoids, and the ratios and differing levels of these cannabinoids (including the 3 major ones in CBN CBD and THC) cause the differing levels of effect.

THC effects receptors in 3 different parts of the brain. The other cannabinoids have an effect on THC, not on you. So differing levels of cannabinoids may effect which receptors the majority THC binds to.

This is speculation though. Hopefully someone else can come clarify.

 

[Nosferatu]

Hmmm....makes sense.

 

[Persona Non Grata]

terpenes

 

[OO]

my understanding is that different cannabinoids activate the same receptors, yet some have different effects on the same receptors which means that inhaling them over a graduated spectrum (I.E. slowly turning up a variable temp vape) would fill up the receptors with one cannabinoid before the other would have the chance to vaporize. this would account for the differance.

i have two vapes, one is a glass straw in which i use a lighter to conductively heat the herb, and it boils off nearly all of the cannabinoids in a couple draws.

the other is the herbalaire, which i use to boil off different cannabinoids as i slowly increase the temperature.

the effects differ greatly with the same bud, that would mean that there is more at work as you have suspected.

the glass straw effect is vividly similar to smoking, the herbie is much different(peaks below a smoking high (unless i turn the temp up all the way from the start)).

 

[Elluzion]

i'm really curious about CBN high strains because the high is supposed to be completely different from a THC high, and all plants these days are working on maximizing the THC content while CBN still stays low. I will be trying Harlequin from SFSPARC soon, can't wait. I will try to report back the effects

 

[Nycdeisel]

Content of different cannabinoids.

Elluzion let us know how that is! I was looking at that strain and wish I had access to it! oh well, enjoy it!

 

[herbgirl]

other chemicals can cause the strains to be unique as well. the more citrusy scented/flavored ones have limonene in them and imo tend to be 'up' type effects.

i understand that the strain called lavender is named so because it smells like lavender and is particularly relaxing. I will assume that this is due to the linanol content, this chemical tends to have a calming effect.

 

[VapeHead.com]

Yep ratios of cannabinoids, terpenoids, flavinols etc.

Also if you're vaping then the temperature at which you vape, and also the rate of change of that temperature over time, affects the high.

e.g. Starting at low temps working up to high temps gives you all of the most volatile oils (flavinols and terpenes) along with mosty THC as it is decarboxylized. Later on you'll start getting the CBDs while you're getting the remaining THC. However if you change temps over time quickly then you'll be getting different effects than if you chang the temperature slowly, or not at all in a single session.

 

[the_germinator]

The variations in the effects of different cannabis strains are caused by the different ratios of cannabinoids and pharmacologically active essential oils found in each cannabis strain. The variance in these essential oils is one of the primary causes for why different cannabis strains produce individual effects. It's possible that certain essential oils in cannabis lose their effectiveness when taken continuously over time, but this has not been proven in research studies.......

I read this on another post- by Lwein, from his dispensary, CRC....

 

[OO]

However if you change temps over time quickly then you'll be getting different effects than if you chang the temperature slowly, or not at all in a single session.

I believe my input on this gives a highly plausible explanation as to the cause of this effect, check post #5 for that info.

 

[Qbit]

i'm really curious about CBN high strains because the high is supposed to be completely different from a THC high, and all plants these days are working on maximizing the THC content while CBN still stays low. I will be trying Harlequin from SFSPARC soon, can't wait. I will try to report back the effects

CBN is cannabinol, which is what THC mostly degrades to when exposed to too much light and air, or when you harvest too late (you'll find high levels in those brown hairs). CBN isn't what you're after.

You're thinking of CBD, or cannabidiol, which has a sedative effect. And the push has generally been to maximise the CBD content, not minimise it.

 

[VapeHead.com]

However if you change temps over time quickly then you'll be getting different effects than if you chang the temperature slowly, or not at all in a single session.

I believe my input on this gives a highly plausible explanation as to the cause of this effect, check post #5 for that info.

It's certainly plausible, but progressive decarboxylation and the presence (or absence) of the more volatile flavinoids and terpenoids is probably having a greater influence than receptor action.

I find the latter gives the most variation in effect, it really encourages a racing sativa-like high in most cannabis regardless of strain, if you're keeping temps down at 170-180 and your herb is fresh and properly cured/stored. Progressive decarboxylation is very apparent in the Volcano, and the iolite in particular seems to over-represent indica-like highs.

Their relative ratio seems to be more important than receptors getting blocked by 1 type for a time, particularly as most of the volatiles are not active at CB1 and CB2 receptors. The interactions are pretty complex and subtle, you've got action at u-opiod receptors, serotonin gets involved, dopamine and hundred more I'm sure.

I'm no expert, you could certainly have described the action of partial vs. full agonists (which is why K2 kills tolerance and is probably more "dangerous" than endogenous and cannabis based actives) but I don't believe it will be playing as large a role.