I wonder if your Rasp Kush was super high in THC? Or maybe you were a bit dehydrated to begin with? I get really extra dry cotton mouth when I overdo it with edibles. A little science behind it.
Cannabis gives you cottonmouth because compounds in the herb interact with cells that control saliva secretion. When inhaled, the primary psychoactive in the herb,
tetrahydrocannabinol (THC), connects with special cell sites called
cannabinoid receptors.
THC is one of a group of over 100 different chemical compounds in the cannabis plant called
cannabinoids.
Different types of these receptors are found throughout the brain and body. It’s the interaction between chemicals in the cannabis plant and these receptors that produce the therapeutic and psychoactive effects in cannabis.
There are cannabinoid receptors on the salivary glands in the mouth. When inhaled, smoke or vapor containing cannabinoids and beneficial aroma molecules called
terpenoids interacts with the tissue in the mouth first, prior to being absorbed by the lungs and taken into the bloodstream.
When compounds like THC engage with cannabinoid receptors in the mouth, they reduce the flow of
saliva and give you cottonmouth.