Phytocannabinoids are cannabinoids that occur naturally in the cannabis plant. The classical cannabinoids are formed through decarboxylation of their respective 2-carboxylic acids (2-COOH), a process which is catalyzed by heat, light or alkaline conditions.
There are also endocannabinoids produced in the human body, which are neither phyto- nor synthetic.Phyto just means from a plant or plant related. So any naturally occurring (read non-synthetic) cannabinoids are phyto-cannabinoids.
Sorry to derail a bit, but are you referring to this mouse study I linked in the AS thread? My understanding of that study was that the mice that had certain gene changes (some with a a particular deletion and some with a particular substitution, both of which mimic AS phenotypes in humans) had deficient tonic endocannabinoid signaling.People with autism spectrum, for example, seem to have a segment of receptors that need cannabinoids, but can't make them naturally (there's a study I skimmed off an AS site...). So, the phytocannabinoid from cannabis, for instance, can fill in those gaps, and balance function.
http://www.letfreedomgrow.com/cmu/GSCListJan2014CONDITIONS.pdfHow do phytocannabinoids help someone with a cell disease
Yes, that study.Sorry to derail a bit, but are you referring to this mouse study I linked in the AS thread? My understanding of that study was that the mice that had certain gene changes (some with a a particular deletion and some with a particular substitution, both of which mimic AS phenotypes in humans) had deficient tonic endocannabinoid signaling.
I took this to mean not that there was a deficiency in the number endocannabinoids produced, but that the "infrastructure" for transporting these cannabinoids during tonic signaling (that is long term, steady signaling) was less effective.
Interestingly the effect was only limited to tonic signaling and not phasic signaling (that is short term, burst signaling). This marked the first time that a particular protein was found to modulate tonic but not phasic signaling in the endocannabinoid system, and validated the existence of the tonic signaling in the first place as a discrete mechanism.
Sorry again for the derail/tangent, but I wanted to clarify that the situation as I see it is a little more complex than "not enough cannabinoids, need more".
Then again if you're referring to a different study altogether I'd love to see it!
Yeah, the implication as far as treatment is the same either way. Just wanted to set the record straight because I'm nitpicky like that I guess.Yes, that study.
I'd say "yeah, that"... except, okay, you UNDERSTOOD the study way better than I did!
I only picked up on "hey, you are possibly lacking this, and cannabis might help"
My initial thought was that THC & CBD, CBN, etc., are ALL phytocannbinoids, and we all, here on this site, pretty much do have some benefits from them. I was just pointing that point out before we got into deeper waters...