Perplexity "Deep Research" report on Cannabis health effects...

zeebudz

Well-Known Member
Thanks, this search helped me find this article, which supports vaping... https://pmc.ncbi.nlm.nih.gov/articles/PMC4456813/

I'm also interested or wondering in how the negative impacts compare to eating too much sugar, animal fat, etc.... I'm probably doing more harm to my body with sweets/sugar and bacon/fried chicken than dhv and tinctures.
If you are interested in herb vaping studies, here are a couple more for you:

Medicinal Cannabis: In Vitro Validation of Vaporizers for the Smoke-Free Inhalation of Cannabis

Acute Effects of Smoked and Vaporized Cannabis in Healthy Adults Who Infrequently Use Cannabis
 

buford

Well-Known Member
"research-grade cannabis"

This term refers to the standardized weed produced by NIDA that was until very recently the only cannabis that could be used in US cannabis research. DEA was in the process of approving new suppliers in 2021, and may now have done so; it is unlikely that many/any studies have yet been published based on the new sources, if any were ever actually approved.

The NIDA "research-grade cannabis" is well known to be of extremely poor quality compared to legal-state commercial, dispensary, or black-market, weed. Sorry to burst your bubble.
 

zeebudz

Well-Known Member
This term refers to the standardized weed produced by NIDA that was until very recently the only cannabis that could be used in US cannabis research. DEA was in the process of approving new suppliers in 2021, and may now have done so; it is unlikely that many/any studies have yet been published based on the new sources, if any were ever actually approved.

The NIDA "research-grade cannabis" is well known to be of extremely poor quality compared to legal-state commercial, dispensary, or black-market, weed. Sorry to burst your bubble.

The National Institute on Drug Abuse (NIDA) is the sole producer of Cannabis for research purposes in the United States, including medical investigation. Previous research established that cannabinoid profiles in the NIDA varieties lacked diversity and potency relative to the Cannabis produced commercially. Additionally, microsatellite marker analyses have established that the NIDA varieties are genetically divergent form varieties produced in the private legal market. Here, we analyzed the genomes of multiple Cannabis varieties from diverse lineages including two produced by NIDA, and we provide further support that NIDA’s varieties differ from widely available medical, recreational, or industrial Cannabis. Furthermore, our results suggest that NIDA’s varieties lack diversity in the single-copy portion of the genome, the maternally inherited genomes, the cannabinoid genes, and in the repetitive content of the genome. Therefore, results based on NIDA’s varieties are not generalizable regarding the effects of Cannabis after consumption. For medical research to be relevant, material that is more widely used would have to be studied. Clearly, having research to date dominated by a single, non-representative source of Cannabis has hindered scientific investigation.

 

old-fart

Maybe not the oldest, but possibly the fartiest!
well, I guess "research grade cannabis" is better then "sushi grade cannabis"! :-)
 
old-fart,

KingNAB

Member
Manufacturer
This term refers to the standardized weed produced by NIDA that was until very recently the only cannabis that could be used in US cannabis research. DEA was in the process of approving new suppliers in 2021, and may now have done so; it is unlikely that many/any studies have yet been published based on the new sources, if any were ever actually approved.

The NIDA "research-grade cannabis" is well known to be of extremely poor quality compared to legal-state commercial, dispensary, or black-market, weed. Sorry to burst your bubble.
I was working with a company out of CA that was being evaluated for this purpose as a recruiter back in 2019, but I'm not sure if that ever came to fruition or still in the works. Last I knew the only producer was Ole Miss, and I just saw they were awarded another 5 years in 23'. As of right now it seems they are still the only producer. Quite unfortunate that they haven't made it happen even after repeated admissions that they need more diversity in product. It makes you wonder why that is.

Why do I care? I just got back my blood work for my annual physical, and there are few troubling areas that I will talk to my doctor about. I'm going down the internet rabbit hole to see if there is a connection between a few items in my results and cannabis use. So far, nothing concrete, but I'm learning good stuff.
I hope you're able to make the necessary changes to turn your health around. Obviously eating well (walked, swam, flew, grew) and consistent sleep schedule will have the biggest impact on your physical health. Being consistent with WHEN you eat and sleep is going to set your body and bodily processes up for success, especially the older you get.

As far as consumption goes, specifically with vaporization, the lower the temp (I suggest 338f, THC is released at 314) the less impact it will have on your lung health. Your source material (obviously need more studies on this) is going to make a difference as well. Keeping down inflammation through diet and temp can make a noticeable difference. CBD can help combat inflammation as well as certain foods.
Edibles are definitely the "healthiest" option of each consumption, but you have to deal with dosing issues and onset timing.

As for using Perplexity, I've been using it more and more for both simple and complex research and coding tasks, and I'm impressed with the results so far. It's a tool, nothing more.
Love to hear you're discovering the benefits of AI's! Definitely check into prompt engineering, but no need to pay for this.. plenty of resources online. Open AI even has their own guide to help with this. The main limitation people will have with LLMs is their ability to communicate clearly what they want from it.
 

old-fart

Maybe not the oldest, but possibly the fartiest!
Thanks @KingNAB .

No way I will pay for a prompt class. Maybe if I were younger and still working and my employer paid for it, but not my own money! :-)

As for my health, nothing major showed up in the blood work. Just a few items that are borderline. RBC slightly elevated (6.04 where 6 is the high range). It was 6.42 last year and I wasn't vaping then, so highly unlikely vaping is related. My biggest concern is HDL. In 2022 is started to go down (36 from 44) and has stayed below 40 (35 currently). 40 is the lower end of the recommended range. I eat pretty well, take two omega 3 "fish" pills daily, exercise. I also highly doubt cannabis is affecting this, but as I said earlier, I was just curious as to health effects of cannabis that might show in my blood work (not drug use, but how it affects all the stats in general), so I started querying. Thanks for you concern.
 
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