Marijuana and ADHD

BaMbAaAChA

HAKUNA MATATA!!
TruthOnPot.com – Irritability, anxiety, depression, insomnia and mood swings. These problems may seem like just a part of everyday life for some people, but they also happen to be symptoms of a condition known as attention deficit hyperactivity disorder (ADHD).

While ADHD remains a controversial topic in today’s society, scientific research continues to show that ADHD is a very real disorder that can lead to a number of health and social problems when left untreated. Interestingly, research also shows that many patients with ADHD have a tendency to self-medicate through a variety of harmful substances and behaviors.

Is marijuana just another one of these substances? Perhaps not, according to research which suggests medical marijuana might actually be effective in treating this common disorder.

What is ADHD?
ADHD (also known as ADD) is a behavioral disorder that is estimated to affect 6-9% of school children and 5% of adults. ADHD encompasses a wide range of symptoms, which lead to impairments in daily functioning. A large portion of ADHD patients also seem to suffer from other neurological disorders, including bipolar, obsessive-compulsive, depression, anxiety and sleep disorders.

Interestingly, studies show that up to 85% of adolescents with a substance abuse problem suffer from an underlying mental condition and that ADHD patients seems to suffer from substance problems the most. People with ADHD are sometimes referred to as having an ‘addictive personality’ because of this.

The tendency for addiction in ADHD patients can easily be explained by research that finds low dopamine levels to be the underlying cause of this disorder. While stimulant medications – such as Ritalin and Vyvanse – act to directly increase levels of dopamine within the brain, research has shown that most recreational drugs can increase dopamine levels as well, including alcohol, tobacco, cocaine and marijuana.

On the other hand, marijuana has a relatively slight effect on dopamine, which is a probable explanation for its low potential for addiction – studies show that only 1 in 10 marijuana users will eventually develop a dependency.

How Can Marijuana Help?
Research on the use of medical marijuana for the treatment of ADHD is very limited. However, a number of health professionals have recently come out in support for the use of marijuana as a treatment for this disorder, claiming that it is safer and less addictive than traditional stimulant medications.

Doctors who have prescribed cannabis as a non-conventional treatment, such as California paediatrician Dr. Claudia Jensen, have found that it can indeed help patients with managing symptoms of ADHD.

“They don’t have to get stoned – it’s dose-related. But they do get the benefit of being able to focus, pay attention, not be impulsive, not be angry, be peaceful and relaxed and pay attention in school, which helps them get better grades.” – Dr. Claudia Jensen

Interesting enough, while marijuana is known to cause loss of focus and increased impulsivity in recreational users, those with ADHD seem to experience the opposite effect. Unfortunately, a lack of clinical studies prevents most doctors from considering marijuana as a treatment option.

Watch Dr. Claudia Jensen’s interview with MSNBC:

What’s The Evidence?
While studies have yet to be conducted on human subjects with ADHD, a number of preclinical studies provide evidence of marijuana’s potential as a treatment for this disorder.

The strongest evidence comes from research which shows that the endocannabinoid system can influence dopamine levels in the brain and that this interaction might actually be altered in patients with ADHD. Specifically, a study published in 2009 found that anandamide levels – one of the cannabinoids that are naturally found in humans – were higher in patients with ADHD.

This seems to indicate that the human body may naturally produce more endocannabinoids in an attempt to counter the symptoms of ADHD, leading researchers to believe that the endocannabinoid system could be effectively targeted in the treatment of this disorder.

Likewise, researchers have long been aware that marijuana acts to temporarily increase dopamine. Compounds in marijuana seem to do this by interacting with dopamine binding sites, which are found on various neurons in the brain. Commonly prescribed stimulants, such as Ritalin and Vyvanse, work in a similar way to increase dopamine.

Besides raising dopamine levels, studies show that cannabinoid receptors are found in higher densities in areas of the brain that are linked to symptoms of ADHD, specifically the amygdala and hippocampus regions. These regions of the brain are known to play a role in emotional regulation and memory as well as bipolar, anxiety and depression disorders.

In fact, there is strong evidence that compounds in marijuana, including THC and CBD, have anti-anxiety and anti-depressant properties, which suggests marijuana may help with the symptoms of anxiety and depression that ADHD patients often suffer from.

Watch Dr. David Bearman’s explanation of the neurological evidence:


What This Means For Your Health
While research on medical marijuana and ADHD is still in its early stages, the fact remains that patients with ADHD have a higher tendency to abuse drugs, marijuana included. Furthermore, there are a number of doctors who have already begun to prescribe medical marijuana as a treatment for this disorder, suggesting that preclinical studies provide enough evidence to satisfy the minds of at least some health professionals.

It’s also interesting to note that prescription ADHD medications have been met with controversy ever since they were introduced to the market, due to their numerous side-effects as well as studies that demonstrate long-term use to be ineffective. In fact, a study published in 2012 by Dr. Katya Rubia and her team of researchers found that the brain can adapt to regular use of stimulants by increasing the rate of dopamine elimination, which explains why patients frequently require higher doses as their treatment progresses.

“There is currently no evidence for the long-term effectiveness of stimulant medication. In fact, there is evidence that the effect of medication diminishes over time and we know from clinicians that medication doses often need to be increased over time to be as effective as they were initially.” – Dr. Katya Rubia

The fact that children are the most likely to be diagnosed with ADHD is perhaps the largest concern for parents and doctors alike regarding the use of stimulant medications. The brain experiences rapid development before adulthood and is highly susceptible to alterations during this time. While studies have identified the specific alterations that result from the use of stimulant medications, evidence of marijuana’s effects on the developing brain are less pronounced.

For this reason, doctors are sometimes willing to prescribe medical marijuana for ADHD as a safer alternative to conventional forms of therapy.

note, original link :

http://www.truthonpot.com/2013/04/01/medical-marijuana-and-adhd-the-facts/
 

biohacker

H.R.E.A.M
Thanks for posting this! I just came across this researching Bipolar disease. I have recently been diagnosed as Bipolar 2 and ADHD, but also have severe crippling insomnia/night sweats, mood disorder, anxiety/depression, and irritability. It's been a lifelong constant struggle of shit and just now, at 40, have I become aware of my reality. I have been self medicating for well over a decade now, exclusively vaporizing only, and over the past 3 years my usage has skyrocketed to 2g/day, and my sleep has become worse. I'm not sure if this is all stress and PTSD related to a highly stressful rotating shift career, but I haven't been working in 6 months, and my sleep has not yet improved. At this point though, I have to again re-evaluate my relationship with vaping, as all my doctors are pushing anti-psychotic meds and mood stabilizers. I tried some Seroquel one night, and it put me to sleep for a solid 7 hours and very little night sweat, but the side effects are insane!

I think all my negative experiences with cannabis have to do with the potency of the THC, and how large of a dose I use, so i'm now being more smart about it, and tapering down THC from 20%+ down to a more reasonable 5%, with more focus on CBD and see what the results are.
 
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farscaper

Well-Known Member
Thanks for posting this! I just came across this researching Bipolar disease. I have recently been diagnosed as Bipolar 2 and ADHD, but also have severe crippling insomnia/night sweats, mood disorder, anxiety/depression, and irritability. It's been a lifelong constant struggle of shit and just now, at 40, have I become aware of my reality. I have been self medicating for well over a decade now, exclusively vaporizing only, and over the past 3 years my usage has skyrocketed to 2g/day, and my sleep has become worse. I'm not sure if this is all stress and PTSD related to a highly stressful rotating shift career, but I haven't been working in 6 months, and my sleep has not yet improved. At this point though, I have to again re-evaluate my relationship with vaping, as all my doctors are pushing anti-psychotic meds and mood stabilizers. I tried some Seroquel one night, and it put me to sleep for a solid 7 hours and very little night sweat, but the side effects are insane!

I think all my negative experiences with cannabis have to do with the potency of the THC, and how large of a dose I use, so i'm now being more smart about it, and tapering down THC from 20%+ down to a more reasonable 5%, with more focus on CBD and see what the results are.
cbn helps with sleep. you can convert high thc strains down to cbn easy since oxidation of thc is what creates cbn.

rosin chips are a good source of cbn as well as low temp abv.

use in moderation. excessive high cbn cbd use may cause some mild anxiety and irritability. but its something you can keep in check with inclusion of thc when the negativity kicks in.

what if the 1 in 10 that "become dependant" simply means 1 in 10 people who try cannabis actually need it for one reason or another.

endocannabinoid homeostasis = goal
 

biohacker

H.R.E.A.M
Thanks bro, i've heard much about the CBN helping. Thing is, I have some capsules with THC, CBD, and CBD but they don't seem to have much of an effect? I remember taking like 4-6 of them a couple of years ago and was really feeling it like an edible! Even with months going by, I try taking 10 of them and feel next to nothing. It's been a while, so perhaps i'll pop a couple before bed, but I don't like putting them through my digestive system.... not sure if edibles really agree with me "overall".

I have zero experience with Rosin, and concentrates are not a staple in my diet due to cost, tolerance, and I i'm certain they don't help my night sweats, however i'm reading up on it and keeping an open mind.

You're completely correct, I feel like I have been self medicating for years, and it's starting to make sense to my why, especially over the past few years....very sleep deprived, nearly lost the ability to sleep due to rotating shifts, and vaping allowed me to get through it all (barely). Unfortunately, I think there is still a cost to pay, as cannabis is still a powerful drug, and I don't know of any drugs that do not have any side effects.

My biggest issue that is bothering me now is night sweats, and it's been this way for a very long time now, and i'm 99% certain it's due to excessive vaping, dependence, tolerance, and possibly very high THC strains. I've tried to rule out so many things, but vaping is the last variable. Instead of cold turkey, i'm restructuring my relationship, and it's only been 3 nights so far.....but OMG....

IT'S WORKING!!! Once again, I was at 1.5g yesterday instead of my usual 2g, and my vaping window is compressed from 11am-5pm now instead of say 5-6am-8pm, and it's actually difficult for me to get the 1.5g in, but I try to avoid withdrawal symptoms and it's working. I'm sleeping BETTER, noticing some odd things like the odd dream, nocturnal erections (giggity!), and waking up feeling REFRESHED! Damn did I miss this! The only time i've experienced this kind of sleep and refreshed feeling after after a long T-break. I am sweating extremely heavily, but still thinking it's a withdrawal symptom.

My bipolar is in a normal cycle and ADHD is in check....I feel CALMER during the day, much happier, and basically like a different person. I can't even believe it! Just need to use weed as a tool, and I think i've finally cracked it.
 

farscaper

Well-Known Member
Thanks bro, i've heard much about the CBN helping. Thing is, I have some capsules with THC, CBD, and CBD but they don't seem to have much of an effect? I remember taking like 4-6 of them a couple of years ago and was really feeling it like an edible! Even with months going by, I try taking 10 of them and feel next to nothing. It's been a while, so perhaps i'll pop a couple before bed, but I don't like putting them through my digestive system.... not sure if edibles really agree with me "overall".

I have zero experience with Rosin, and concentrates are not a staple in my diet due to cost, tolerance, and I i'm certain they don't help my night sweats, however i'm reading up on it and keeping an open mind.

You're completely correct, I feel like I have been self medicating for years, and it's starting to make sense to my why, especially over the past few years....very sleep deprived, nearly lost the ability to sleep due to rotating shifts, and vaping allowed me to get through it all (barely). Unfortunately, I think there is still a cost to pay, as cannabis is still a powerful drug, and I don't know of any drugs that do not have any side effects.

My biggest issue that is bothering me now is night sweats, and it's been this way for a very long time now, and i'm 99% certain it's due to excessive vaping, dependence, tolerance, and possibly very high THC strains. I've tried to rule out so many things, but vaping is the last variable. Instead of cold turkey, i'm restructuring my relationship, and it's only been 3 nights so far.....but OMG....

IT'S WORKING!!! Once again, I was at 1.5g yesterday instead of my usual 2g, and my vaping window is compressed from 11am-5pm now instead of say 5-6am-8pm, and it's actually difficult for me to get the 1.5g in, but I try to avoid withdrawal symptoms and it's working. I'm sleeping BETTER, noticing some odd things like the odd dream, nocturnal erections (giggity!), and waking up feeling REFRESHED! Damn did I miss this! The only time i've experienced this kind of sleep and refreshed feeling after after a long T-break. I am sweating extremely heavily, but still thinking it's a withdrawal symptom.

My bipolar is in a normal cycle and ADHD is in check....I feel CALMER during the day, much happier, and basically like a different person. I can't even believe it! Just need to use weed as a tool, and I think i've finally cracked it.
its great you have such a firm grip on your needs. it can be a struggle to keep everything in check no doubt.

I have issues with edibles some times and I try to stay away from them as much as possible. I think edibles slow my digestive system evem more than it already is (an I regularly suffer ibs symptoms) plus if you wanna talk about a tolerance killer, edibles send my tolerance sky high for a week after eating them.
 
farscaper,
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biohacker

H.R.E.A.M
Your words describe the exact reason I don't use edibles anymore. I feel it's really hard on my system.

I'm extremely mindful of my body, but you're right it's a constant struggle. If I could just get over the night sweats, I would be SO happy! Still think it's a withdrawal thing, but won't know for a few more weeks. I sweated during my sleep study, so perhaps they will know or see why.
 

CNYC

Well-Known Member
I think all my negative experiences with cannabis have to do with the potency of the THC, and how large of a dose I use, so i'm now being more smart about it, and tapering down THC from 20%+ down to a more reasonable 5%, with more focus on CBD and see what the results are.

I am 46 years old been combusting since I was 12. Recently got my MJ Recommendation after moving out to California. All I've got to say is WOW this isn't your MJ from the 70's or 80's. I was using CA MJ in NYC but I was sprinkling it on top of mexican shwag and the balance was a nice calming effect. I WISH I had access to crappy mexican weed in San Diego. Too funny but it is true.

I guess for pain management a high dose of THC is necessary but I fall somewhere in between. I was diagnosed with borderline Bi-Polar disorder but also have chronic low back pain. These two issues conflict each other when dosing myself with MJ.

This year alone I have gone overboard...unwillingly on THC so many times it is pathetic. To the point where I question what the F I am doing with this stuff. Then I get the dosage right and it feels so good and RIGHT.

My conclusion after one year of having access to medical MJ is :

1. I can ingest between 5mg to 10mg comfortably (edibles)......not 1mg more.

2. I must have food in my system before I smoke or eat an edible. This stuff is too potent to have on an empty stomach AND you MUST be properly hydrated.

3. *** NO MORE JOINTS BONG HITS OR FULL BOWLS. I cannot stress this enough. I use a tiny bubbler these days. I tear off a TINY piece of bud enough for one little hit put it in the bowl toke up/vape up then wait at least an hour before I even think of doing another hit. *** ONE TOKE at a time.

4. I am now experimenting with 2.5mg of THC to ingest. I used to think 5mg was the lowest I needed but I read somewhere that 2.5mg of THC would also be sufficient for anxiety and my medical needs.


I do miss vaping an entire bowl or sucking down on a joint but I've done that for too many years. Time for a change.

On a more positive note my infrequent alcohol use has become almost ZERO. You cannot mix beer and edibles. You will regret it. The same goes for my occasional cigars....I haven't had one in weeks. It has synergistic effects with THC. Xanax usage this year....maybe a handful of times at .1/4 of a mg. Vicodin usage ZERO. I would be petrified to use Vicodin with high potency THC. Don't do it.

The running joke is GOOD WEED is keeping me from using too much of it ! :)

Be Safe and use responsibly.
 

biohacker

H.R.E.A.M
Totally forgot about this thread! Much as changed for me and continues to get better and better. My night sweats of YEARS has ended! It was my excessive vaping from morning until night that was the cause, and now i'm down to less than 1g/afternoon and evening, and sometimes much less like .5g. No more sweating excessively, smelling like skunk, and most importantly a DRY bed at night! My sleep has improved and i'm so much calmer in the day and in full control of my emotions.

The Bipolar2 is presently being "ruled out" and i'm now down to ADHD and anxiety disorder, and since i've dropped my usage of vaping so much, they dropped "Cannabis Use" out of my diagnoses! lol

Re-evaluating my relationship with cannabis has allowed me to reflect and make some real changes regarding my dosing and i've experienced nothing but positive life changing results! LOVE IT!
 

CNYC

Well-Known Member
Totally forgot about this thread! Much as changed for me and continues to get better and better. My night sweats of YEARS has ended! It was my excessive vaping from morning until night that was the cause, and now i'm down to less than 1g/afternoon and evening, and sometimes much less like .5g. No more sweating excessively, smelling like skunk, and most importantly a DRY bed at night! My sleep has improved and i'm so much calmer in the day and in full control of my emotions.

The Bipolar2 is presently being "ruled out" and i'm now down to ADHD and anxiety disorder, and since i've dropped my usage of vaping so much, they dropped "Cannabis Use" out of my diagnoses! lol

Re-evaluating my relationship with cannabis has allowed me to reflect and make some real changes regarding my dosing and i've experienced nothing but positive life changing results! LOVE IT!

So are you saying that you were over doing it with MJ or that MJ in general was causing you these problems ?
 
CNYC,
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biohacker

H.R.E.A.M
OVERDOING IT BIG TIME!!! The poison is in the dose. I was experiencing side effects because I thought I could vape as much as I wanted without any negative effects. Boy did I ever learn a hard lesson!

Even the slight withdrawal I experienced from cutting back was nothing like withdrawal symptoms i've experienced in the past, going cold turkey.

Cannabis in general has basically been a life saving panacea for me, but I respect the plant and keep a watchful eye on that fine line, and not cross over to it. I also much enjoy my sobriety during the day, and would have to say that my mood is vastly improved, potentially the result of better deeper sleeping.
 

CNYC

Well-Known Member
^ Thanks for posting. I think this stuff is just too damn potent to be honest. I hope I don't sound like a party pooper but I've been trippin balls all day on just a 2.5mg dose of an edible. That is ridiculous. It seems like I can't find a mellow high within all the heavy duty THC laden flower.

To be honest it gets annoying when you are high for 10 hours straight. Smoking/Vaping doesn't do that to me but I've had a chest cold for two weeks so I have been doing strictly edibles. They last too long...even in tiny doses.

Maybe I should follow suite and cut down a lot.

Be Well.
 

biohacker

H.R.E.A.M
Honestly, just IMHO - edibles are NOT for you. It gets processed differently and can be too powerful for some people.

I also neglected to mention a very important detail. I have introduced CBD vaping into my life and always end my night with a high CBD low THC strain, and possibly it's balancing out any negative effects. It's not scientific, but whatever i'm doing now is working very well, and if you look at some of my older posts/thread including night sweats, you will notice that i've been struggling for a very long time.

Best of luck in cutting down, you're right - we have access to some very strong and potent medicine! I love it! lol
 

CNYC

Well-Known Member
I just posted a rather lengthy reply on a CBD thread as to my experiences with it. I don't think it is non psychoactive at all. You can still over do CBD but the effects are more of a body high. Too much CBD is just as bad as too much THC IMO. I have felt those effects as well. :)

You are right about the edibles. Although I need them at times so I can be discreet and the duration does serve a purpose for me when I go down to Mexico ( I live in San Diego) . I don't want to risk smoking down there but YES little tiny hits of low THC weed from my pipe is what I really need.
 

biohacker

H.R.E.A.M
Just read your post over there, and completely agree....even at 0% THC, you can definitely feel the effects of CBD! I think adding the CBD to thc is a good idea, and not only do the CDB..... with so much damn THC in alot of the strains I have (with little to no CBD), it's a good idea to balance it out. I've noticed nothing but positive effects from adding it, now that I have the luxury of even having access to it!
 

CuckFumbustion

Lo and Behold! The transformative power of Vapor.
3. *** NO MORE JOINTS BONG HITS OR FULL BOWLS. I cannot stress this enough. I use a tiny bubbler these days. I tear off a TINY piece of bud enough for one little hit put it in the bowl toke up/vape up then wait at least an hour before I even think of doing another hit. *** ONE TOKE at a time.
You could take it a notch further and get familiar with micro dosing. I know very little myself. But choosing when to dose and when to eat and hydrate, could help with the more medicinal side of the cannibus. You seem like you have a routine down and that might help your system get a balance of sorts.
I have a bubbler that will a lot of draw space after it passes through water and it seems to help me have more control of the strength of the vapor and squeezing the most essence.

Don't pretend to know much about ADHD, more misinformation for me than information. I do believe more science will come along that will help us understand what is a measured dose. But taking a tolerance break just before getting into a project might be a strategy just before the hyper-focus kicks in and time flies by because you are absorbed in a project.

and should I think of ADHD as a condition or differently minded? It seems like more people are self diagnosing themselves with this condition.
 

biohacker

H.R.E.A.M
Unfortunately far too many medical professionals are way too trigger happy diagnosing this condition as well.

What if one is just highly intelligent and bored in school? Must be ADD!
 

h3rbalist

I used to do drugs. I still do, but I used to, too
My 5 year old girl is being assesed to see if she has ADHD or is possibly on the Aspergers spectrum.

One thing I am realising after learning more about these issues is that I possibly fall into the spectrum myself and have been 'self medicating' for many years.

I have always had a high tolerance which I believed to be just from my regular usage but as I have got older it's easy to see it's not quite as simple as that.

It's early days with regards to my daughters diagnosis and I have a long road ahead but I find this link to cannibis thc/cbd fascinating.


I think I am going to experiment with some cbd oil on myself and see how I get on.
 

biohacker

H.R.E.A.M
Sounds like we are very alike.... i've been self medicating for a decade now with vapour exclusively, and combustion before that. I can relate with what you said about tolerance as well. I think perhaps we have dysfunctional endocannabinoid systems and vaping the adaptogenic herb balances everything out, as long as we don't swing to far to the THC side of the spectrum, and perhaps the other way with CBD.

I don't much like CBD without THC! Both are important.
 

Reliable ShotZ

Active Member
I suffer from ADD so badly that I couldn't even read all of the original post. gaming and vaping combined is so soothing for my condition, trouble is I've never been diagnosed throughout my whole life. I have very much gone through life under the radar and I wish I knew about it sooner. I personally think that cannabis has a lot of pros and also a lot of cons. that first hour actually makes it worse but once the high plateaus thats when the calming benefits kick in. Cannabis can make me very forgetful, particularly when Im following non written instructions, of course some of it could be down to ADD but i think its a bit of both. I think chronic use and overdoing it could probably make ADD worse particularly when not using it. Overall I reckon moderate use and making sure you have a decent amount of days off here and there cannabis can benefit ADD greatly and I see it as nice way to switch off and calm the mind once in a while.
 

CNYC

Well-Known Member
You could take it a notch further and get familiar with micro dosing. I know very little myself. But choosing when to dose and when to eat and hydrate, could help with the more medicinal side of the cannibus. You seem like you have a routine down and that might help your system get a balance of sorts.
I have a bubbler that will a lot of draw space after it passes through water and it seems to help me have more control of the strength of the vapor and squeezing the most essence.

Don't pretend to know much about ADHD, more misinformation for me than information. I do believe more science will come along that will help us understand what is a measured dose. But taking a tolerance break just before getting into a project might be a strategy just before the hyper-focus kicks in and time flies by because you are absorbed in a project.

and should I think of ADHD as a condition or differently minded? It seems like more people are self diagnosing themselves with this condition.

Well Said.

I would also like to add that from my experiences doing edibles for consecutive days in a row builds up a residue and you need less to achieve the same effect the following days. Any takers ?

Case in point :

I have had a chest cold for the past two weeks and have not smoked or vaped anything. Maybe two weeks ago I was taking 10mg Dixie Relaxing Mints for roughly one week then cutting down to 5mg....achieving more or less the SAME EFFECT as that of 10mg and the duration was just as long.....fast forward to this week (yesterday) I took 2.5mg of the same edible because I felt a residual hangover from the day before ...and the 2.5mg FLOORED me . I couldn't believe it. Some would say hey that's great but I was more like WTF. The only explanation has to be that edibles build up in your system. I guess some people build up a tolerance with daily use and some go in the opposite direction.

Another common occurrence with me is I will feel great with an edible for roughly 6 hours...even sleep on it then when hour 10 comes along it knocks me upside the head and I am high as F. I just don't get it.

By the way I have roughly 15 years as a Marinol patient so I am very schooled in the art of ingesting THC but this medical stuff is WAY MORE POTENT.

I need edibles in my life so this is a little concerning to me.

Can anyone add to this ? Thanks for posting your thoughts.
 

CuckFumbustion

Lo and Behold! The transformative power of Vapor.
Well Said.

I would also like to add that from my experiences doing edibles for consecutive days in a row builds up a residue and you need less to achieve the same effect the following days. Any takers ?

Case in point :

I have had a chest cold for the past two weeks and have not smoked or vaped anything. Maybe two weeks ago I was taking 10mg Dixie Relaxing Mints for roughly one week then cutting down to 5mg....achieving more or less the SAME EFFECT as that of 10mg and the duration was just as long.....fast forward to this week (yesterday) I took 2.5mg of the same edible because I felt a residual hangover from the day before ...and the 2.5mg FLOORED me . I couldn't believe it. Some would say hey that's great but I was more like WTF. The only explanation has to be that edibles build up in your system. I guess some people build up a tolerance with daily use and some go in the opposite direction.

Another common occurrence with me is I will feel great with an edible for roughly 6 hours...even sleep on it then when hour 10 comes along it knocks me upside the head and I am high as F. I just don't get it.

By the way I have roughly 15 years as a Marinol patient so I am very schooled in the art of ingesting THC but this medical stuff is WAY MORE POTENT.

I need edibles in my life so this is a little concerning to me.

Can anyone add to this ? Thanks for posting your thoughts.
I believe an having some sort of diet and in your case having a chest cold may have been a larger factor. Being outside in the cold affects me.
There is this whole other area of terpenes to consider. I have vaped lemongrass beforehand to see if it has an impact. Aromatherapy is also another field of study relating to microdosing IMHO and regulating your medication. Because essentially you are trying sync up with how your body metabolizes and stretch out your doses for more impact. Even a 4 hour break will give you a small amount of edge. If you are treating your condition and not just going for the euphoric effects, I say go wide and have controls on your diet and exercise and try to bring these things together in a more cohesive manner to get into the habit.
Edibles are hit and miss with me. And the experiences have varied too much to have a sort of control on it. The simpler the recipe, the easier it might be to factor dosage.
 

biohacker

H.R.E.A.M
@CNYC My experience with edibles is the opposite - my tolerance creeps up greatly, and they lose their effect. It also makes me feel sluggish and burnt if I do them regularily. Must not enjoy that since I haven't touched an edible in years. Like @CuckFumbustion said, the effects are hit and miss with me as well, and the experience varies.

What is Marinol like? I've always thought about it, perhaps for sleep?
 
biohacker,

CNYC

Well-Known Member
Marinol is basically synthetic THC wrapped in a sesame oil base. It too has a mind of its' own. Sometimes it works beautifully but other times it is a dud. The effects only last 4 hours. The biggest PITA is it has to be kept at a certain temperature or else they melt or lose potency.....try doing that while traveling ! * The beauty of Marinol is it is legal. Go figure...synthetic THC is legal but the real stuff isn't because it has no medicinal value. What a crock of shit.

Lots of stoners say Marinol doesn't work and they took 5 pills with no effects. I say nonsense.


The other downside to Marinol is the cost. My insurance just dropped it from the formulary list after 15 years. A month prescription on the low end is $1,300 upwards to $4,000...PER MONTH. I could survive 3 years at my local dispensary for that money.
 

CuckFumbustion

Lo and Behold! The transformative power of Vapor.
@CNYC thanks for setting it straight with Marinol and the business side of it. :tup:And unfortunately your current situation. :ugh:

Is there any advantage of using Marinol over an alternative then say regulated doses? I'm trying to justify the price tag and processing. I know about more misinformation than information on Marinol on all sides atm. And not up to speed for that matter. I didn't even realized their were still patients for it.

Is it a situation of it being all that processing and expense to reinvent the wheel? Or it there an advantage enough like Say regulated doses? I am in more than one mind with Cannibus and the complex compounds that are produced. Your take would help me rethink even more with all the new science coming out. TX
 
CuckFumbustion,
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