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Very impressed by the Reload Gen 2. The coating is perfect, the threads work well, the new debowling spike is a nice improvement, the increased capacity is great, and the best thing is now being able to rest your TED horizontally on the top. Highly recommended. Thankyou @Brenyo !

There are herbal possiblities and I hope that a suitable remedy can be found, but antiplatelet drugs all have side effects (some potentially fatal). Changing prescriptions adds more complication, combining them can be dangerous, and not taking them when prescribed can also be fatal, so great...

PSA: Ibuprofen is fine for short term use, and necessary for extended use when directed by a physician, but dependency is possible and one should not come to rely on the drug. And GoldenBud's enthusiastic recommendations are a recipe for creating more members of the Reddit Weed PAWS club.

I didn't enter this thread for an argument and I didn't read your posts before starting, but in other places you have said that you took Ibuprofen (up to 1200mg daily, the maximum recommended dose) for 40-50 days, which is enough to cause dependency. And your headaches (a common side effect) and...

@GoldenBud Perhaps we are close to agreement on some aspects of the chemistry of THC, but on PAWS and Ibuprofen we are still far apart. I have met thousands of regular (recreational or religious) Cannabis users, and over the years many have stopped using (including myself) but I have never...

The structure of THC is similar to anandamine, but it's action is more complex than a simple replacement. Interesting articles. So THC, acting through cannabinoid receptors, subsequently activates the brain’s reward system, causing higher levels of dopamine. Anandamide and THC serve as an...

You can't get addicted to Ibuprofen, but it can cause dependency, and overdose can be fatal. The common side effects of Ibuprofen include headache, restless sleep and sweating. So anyone using Ibuprofen to withdraw from Cannabis should seriously consider that Ibuprofen rather than Cannabis could...

Prasugrel is a thienopyridine, a platelet inhibitor and an irreversible antagonist of P2Y12 ADP receptors. Ticagrelor has similar indications for use but it differs from thienopyridines by reversibly (rather than irreversibly) inhibiting the P2Y12 receptor. Ticagrelor seems to have less side...

I love my Zob Zobello Klein Recycler, and the Goo Roo Klein Recycler also looks like a great option (it's on my VAS list).

If addiction is "neurologically/psychologically driven" and dependence is "one's body needing something", then the distinction is really not clear. And gambling "addiction" and opiate addiction are fundamentally different things. Gambling is not a physical addiction in the same way as opiates...

I did say that "addiction has primary physiological causes, and if you take enough opiates (for example) you will become addicted". And anything that causes dopamine to spike can cause a dependency. And THC causes deeper sleep, so you are less likely to become aware in (or just after) REM sleep...

The term "addiction" is thrown around loosely, so I thought it was important to consider it's definition, and an important point is that an addictive drug will cause an addiction while a drug that can cause dependency may cause an apparent addiction. THC can cause dependency, so only some users...

Lured in by an interesting survey, my use of the survey's own words has been questioned, and every point made has been misunderstood. :horse:

Ibuprofen can cause dependency, and Ibuprofen can kill you.

In Australia voting has become synonymous with the "democracy sausage", which is offensive for vegetarians. Voting is compulsory, but it requires passing through the stench of a cremation ground.

The first part of my post was factual, and the second part was personal opinion. I haven't noticed any improvement to my life when not using Cannabis, but not smoking it has led to great improvements. I am well aware that years of smoking have left me at risk of various problems. And mental...

Fuck Combustion is a haven for good information and interesting discussion on all aspects of non-combustive consumption, but some posts seem like Reefer Madness!

Hooray! Just got notification that my Reload should arrive next week.

Addiction can be entirely physiological and dependence can be entirely psychological, but in both cases there may be a mixture of physiological and psychological effects. Addiction has primary physiological causes, and if you take enough opiates (for example) you will become addicted. Dependency...

No need to inhale anything if you eat it. Try bhang instead.