Cannabis most definitely can make depression significantly worse for some people. That can be a result of it worsening the feelings themselves, and/or being used as a crutch which can often make symptoms much worse when the high goes away. What about the fact that it's supposed to ease anxiety/stress, but can also raise both of those things to unbearable levels for some people. There are lots of people who won't use Cannabis because it makes them feel terrible. Does that make it a logical fallacy to prescribe it as a potential treatment for those things? Every drug has different effects on each individual, especially when it comes to psychiatric issues. As for Cannabis and the ECS... there seems to be an assumption here that Cannabis use balances our ECS. That's not necessarily true. It affects it, obviously, but doesn't necessarily balance it. That would take consistent dosing at a specific amount, in people who have hypoactive EC systems to begin with. Consuming cannabis whenever you want, and getting buzzed from it, is not causing perfect homeostasis. IMO, it's more likely to be putting it into overdrive than balancing it. If you don't have a hypoactive ECS, you are enhancing an already balanced system by ingesting extra Cannabinoids. Homeostasis doesn't cause a buzz. Depression, euphoria, buzzing sensations, enhanced relaxation, etc., are all signs of being out of homeostasis. Because chemotherapy saves lives. There are thousands upon thousands of people who would have died without chemotherapy. The modern medicine hate on this forum is ridiculous.