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Cannabinoid hyperemesis syndrome

Discussion in 'Medical Discussion' started by Nosferatu, Nov 30, 2012.

  1. hibeam

    hibeam alpha +

    Brave New World
    Flawed studies like the above about CHS deaths can make me turn to bro science like this that at least tries to be scientific:
    asdf420, Demontrich and biohacker like this.
  2. chris 71

    chris 71 Well-Known Member

    Here is a better link about capsaicin cream and why it and the hot shower thing might help .


    I still think we cant be sure it is from the canabiniods but maybe it is . i have been wondering more and more if i sometimes experience the prodormal phase of this
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  3. bara

    bara Well-Known Member

    Developed this 4 years ago and have stopped until now. Really need it for my depression, and it's working very well. But def still have CHS. pretty annoying disease.

    I was not a heavy user by any means. Never had dabbed. Used mostly edibles during the last several months before I left the country. Came back, started vaping a bit and started shortly after. Def a very light user, but got it just the same. I'm experimenting and trying to figure out how to deep cannabis in my life, but it has been difficult thus far.

    Edit: capsaicin cream on the stomach provides minor relief. I grow ghost peppers and will aggravate and then see which provides more relief tomorrow.
    Last edited: Oct 8, 2018
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  4. BornAgainSteama

    BornAgainSteama I'm proud to be a stoner, yes I am.

    I have been diagnosed with CHS for a couple years but have had the condition about four years.

    I can only speak from my experience so disregard what you want.

    I have noticed that I have a specific type of nausea that accompanies my CHS. It has a unique feeling with urges to take hot baths. My attacks go for about 12 hours of severe hyperemesis and several have ended up in the ER. If you end up in the ER I have read benadryl and thorazine (chlorpromazine) can help (I use benadryl for CHS regularly). If you have used benadryl it is of the upmost importance to inform your ER technician of the benadryl dose you have been taking before you take thorazine. benadryl and chlorpromazine have drug interactions. Click her for more info.

    After awhile I began to discover when an attack was about to happen the specific nausea is key. When or if you feel this type of nausea begin you need to stop everything you are doing.

    1. Do drink fluids if at all possible
    2. Do not eat
    3. Do not use herb (your body has had enough and needs a short break)
    4. Do take some benadryl once you notice any nausea
    5. Go ahead and take a hot bath if you feel it will help prevent you from vomiting.
    6. If you have been vomiting for hours go to the ER because it is an emergency

    The main thing to know is not to let the vomiting begin. Do everything it takes to not allow the vomiting cycle to begin.
    Once vomiting begins for me I am in for about 12 hours of complete hell.

    I have been doing these avoidance techniques for about a year and have not had a CHS attack because I know when they are coming and I know what to do to prevent them. It all has worked out better than I would have ever thought possible. Knock on wood. It is likely I will have another event at some point in my life but I have learn how to control it for now. I still use herb all the time too while using these techniques. I just take short day or two long breaks if I feel that special CHS nausea. That's all a couple day T-break for me to avoid the nausea completely.

    Good Luck to you and anyone else that has had to experience CHS. Of course results won't be the same for all people but there is some light at the end of this tunnel for you imo.

    EDIT: Also this

    Haloperidol, a Novel Treatment for Cannabinoid Hyperemesis Syndrome.
    Cannabinoid hyperemesis syndrome (CHS) is typically unresponsive to conventional pharmacologic antiemetics, and patients often require excessive laboratory and radiographic testing and hospital admission. We report 4 cases of CHS that failed standard emergency department therapy but improved significantly after treatment with haloperidol. Although the exact mechanism for CHS remains unclear, dysregulation at cannabinoid type 1 seems to play a role. Recent animal data demonstrate complex interactions between dopamine and cannabinoid type 1 signaling, a potential mechanism for haloperidol success in patients with CHS. Our success with haloperidol in these 4 patients warrants further investigation of haloperidol as an emergency department treatment for CHS.


    Last edited: Oct 10, 2018
  5. bara

    bara Well-Known Member

    Thank you so much for this info. It gives me hope hearing you can still use! I'll def keep all this in mind.

    Does anybody know if different cannabinoids are worse than others?

    I have a theory that cbd is the worst. I have a cbc and cbg cream, and it still can push me over. But pure cbd cream is really bad. I think the cannabinoid count in cbc was higher as well.
    BornAgainSteama likes this.
  6. BornAgainSteama

    BornAgainSteama I'm proud to be a stoner, yes I am.

    I think this whole thing is very new so I doubt they have been able to pin down a cannabiniod, cause, or specific origin.

    What they do know is that all CHS patients have extreme nausea, hyperemesis, and an unrelenting urge to take hot baths, and last but not least a cannabis habit. Anyone with these symptoms gets the tag CHS.

    They will learn more over time, but the fact cannabis is illegal on the federal level prevents needed research.
    Vapeur Rogue likes this.
  7. asdf420

    asdf420 Well-Known Member

    I've gotten nausea from vaping CBD.. I'd like to fuck with CBC and CBG more, CBD just doesn't seem good
  8. bara

    bara Well-Known Member

    I don't have the shower thing, but I def have the rest.

    I have been experimenting with eating ghost peppers to calm symptoms. It does help a little bit, but It can be tricky because cap can cause pain and vomiting. It also only seems to help so much. I also have hppd, so I can only smoke a small amount anyway.

    It also seems that cedarwood and especially sandalwood agro my symptoms pretty badly.

    Some of my experiments going forward are going to involve growing my own product to see if that reduces nausea, and experiment with smoking as compared to vaping.

    I also want to comment on your protocol for chs management born. I seem to actually get worse after a couple days. It seems if I feel the chs while smoking, I should shut down but don't always. two days after is generally really bad, and the third is either a bit worse or better. by the 7th day it starts to inch towards completion of the pattern, but by that time it's my time off and I need to vape again for the sake of my sanity, unfortunately.

    I am hoping that if I can abstain for few weeks i'll be able to develop a better pattern. If I complete this goal I'll see if I can get to a place like born is at.

    I also want to mention I am using a very small amount. vaping like...maybe .05? It's an elbow pack into a vape.
    Last edited: Oct 23, 2018
  9. Garysfriend

    Garysfriend Well-Known Member

    Hey everyone,

    I've posted in this thread a few times before regarding stomach issues and cannabis. Over the past 3 years or so I've had a few episodes where for weeks (or up to a month or two) any time I would vape I would get stomach pain and nausea, usually shortly after that would last through the evening into the next day. I'm not sure if it's CHS, as I never vomited, and I don't really get the urge to shower. Showers feel good, but that's about it. I've also tried that capsaicin cream which doesn't seem to do much.

    Anyway, I was thinking about something. And I realize this may not pertain to those of you who have the full blown CHS symptoms (and I really feel for you guys), but my stomach issues always come about during the late fall, winter or early spring. I live in the Northern part of the US, and work your typical office job, inside all day. From October to April I get very little natural light. My most recent episode which started a week ago caused me to go into research mode again, and in several instances I saw that low vitamin D can cause digestive issues (it's actually thought to be linked to IBS). I'm wondering if cannabis can exacerbate a low vitamin D issue? I am currently on a break, and have started to take vitamin D supplements (along with E, B complex, and magnesium which I've read could be helpful to any cannabis user) and I've noticed my mood and energy have greatly increased in just a few days.

    So, I know this may not pertain to many of you, but I just wanted to share my thoughts. For those of you suffering have you had your Vit D levels checked recently?

    Another thought of mine has been the presence of candida or other fungus/parasites. I recently got super sick from eating at Chipoltle, and had to be put on antibiotics after non stop diarrhea (which eventually turned bloody) for a week. Now I know I'm expressing symptoms of candida, which is known to occur after heavy use of antibiotics (I was on two drugs for two weeks). Shortly after the antibiotic course I started having stomach issues when vaping. Not sure if it's a coincidence or what. I don't know if there is a link between messed up gut microbiome and cannabis stomach problems, but I'm trying to figure that out, and fix myself at the same time.

    Again, I understand this may not be helpful to those who have full blown CHS, and I don't think I really do, but cannabis does give me stomach issues from time to time. Just wanted to share my thoughts and hopefully we all can continue to learn.
  10. BornAgainSteama

    BornAgainSteama I'm proud to be a stoner, yes I am.

    If you do not experience intense protracted vomiting, hyperemisis, and the hot bath compulsion then you don't yet have CHS.

    The important thing to remember about CHS is to do everything you can to not begin vomiting. Once the vomiting cycle begins it is not likely to stop for a very long time and it is extremely intense. You will feel like dying.

    Another problem is that because cannabis is illegal federally things like CHS are difficult to research in scientific studies with control groups and the like. All we have is pretty much is emergency room anecdotal evidence. We can't truly study CHS without legal access cannabis. Sad.

    Last edited: Nov 8, 2018
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  11. Garysfriend

    Garysfriend Well-Known Member

    BornAgainSteama, I hear ya. I don't think I have CHS but cannabis does bother my stomach, usually an hour after vaping and into the next morning. 3rd time about 2 years. It's been a while since I've read through this entire thread but I believe there were a few others who were similar to me, or maybe didn't have as severe symptoms.

    There are a few theories out there on what's causing this but nobody really knows for sure. My thoughts, at least for maybe a few of the people out there, is that it could be a vitamin deficiency, or possible bad gut bugs. While it may not be the most credible source, I recently read a Reddit post where some guy was diagnosed with CHS at the hospital, only to find out later he had a stomach parasite, that would just irritate his gut when he smoked. They got rid of the parasite and he was good.

    For me, I tend to develop symptoms when I've done something I know is not good for my overall digestive health, in this case antibiotic use.. or in the late fall, winter or early spring when I get little natural Vitamin D. This has never happened in the summer, or when I know my digestive health is very good.

    So I just wanted to share my thoughts, see if that helps connect the dots for someone else. Unless it's a neem oil poisoning situation, I tend to think CHS is a symptom of an overall larger issue in the body. It just takes cannabis to bring those symptoms out. But I'm just some guy on the internet.
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  12. BornAgainSteama

    BornAgainSteama I'm proud to be a stoner, yes I am.

    I can tell you 100% it is not a vitamin deficiency or a gut crazy tapeworm...LMAO! Very funny!

    I think you are right that there is something that is causing the CHS reaction somewhere in the body or even in the brain because of the vomiting evidence. It has something to do with the inability for a person to shutdown the vomiting cycle controlled in the brain so extreme vomiting goes on for hours and hours.

    CHS is not a stomach ache, CHS is truly a hell on earth. It gives me chills just recalling the last time it kicked my ass. Very intense and scary shit no doubt about it.

    There is no doubt a serious attack of CHS could kill a person. Vomiting for up to twelve hours can easily kill a person. People can die from dehydration when they intensely vomit for that amount of time.

  13. chris 71

    chris 71 Well-Known Member

    Steama , do you remember noticing any prodormal symptoms when you went through this ? Did you have and bowel symptoms ? There is supossedly a prodromal phase that people experience .
    sometimes for months or even years before the full on hyperemesis phase .
    And the compulsion to have a hot bath is suppossed to be a learned behaviour.

    I would think maybe because the person feels cold or something in there extremities maybe from the blood going to the gi tract in preperation for the purge of vomiting to come ?

    All just speculation here ofcoarse but i just wonder if you or anybody eles that has been through this remembers the prodromal phase and what the symptoms were ?
    BornAgainSteama likes this.
  14. Garysfriend

    Garysfriend Well-Known Member

    chris71, do you think you have CHS, and if so what are your symptoms? I'm still trying to figure out if this is what I have.

    I get stomach pains within 30min - 2hrs of vaping. It will then last all through the night and into the next day. Eventually the nausea starts to accompany the stomach pain. I will also usually feel bloated. I haven't vomited, and don't know if I would if I continued to push it. Once I start getting these warning signs I take a break.

    I rarely vape more than .1g in an evening, but I've been doing this for 10+ years. I just find it so odd that all of a sudden this would just start happening. When my issues started this time around (a few weeks back), it was with the same stash I've been using for the past 3 months without issue. Odd.

    I stumbled upon this a few days back. Don't really know yet what to make of it, other than it's some pretty poor web design. http://www.marijuana-syndromes.com/ He briefly touches on stomach problems, (see his earth pathology segment). I know nothing about qi-gong, but figured I'd start giving it a try? I guess I'm just desperate at this point to get back to my evening routine, even though seems a bit, well... silly?
    BornAgainSteama likes this.
  15. chris 71

    chris 71 Well-Known Member

    I have wondered a time or two if i could be getting the prodromal phase. . but i havent actully thrown up in as long as i can remember im talking like decades lol

    I have other issues that are most likely the cause of my problems i think .

    i have been taking medication for graves disease for a little over 2 years . the side effect of the med and the disease both can involve lots of sick feelings so in my case i think that is most likely my problem .

    But every once in a while i will get a feeling like i might puke after i vape .or other times when not vaping at all . and thanks to this thread and stories of scromiting i get a little paraniod that im might start non stop puking lol

    I know its no joke for people that this has happened too , and i hope to hell it never happens to me . but i do wonder sometimes when i get this sick feeling .

    Iv noticed that most of the time this sick feeling is followed by a bowel movment and then i feel better almost instantly .

    but then it can happen for a few days and a few times a day . and my guts just seemed really messed, heart burn bloating and all that junk.

    I just wondered if this is any kind of symptom others have had before the vomiting starts . i sometime feel if the bowel movement did not come i would puke .

    Im still on the fence about weather i think it is form canabinoids and should even be call as such. because there could be soo many other things involved pesticides, fertilizer molds ect ect

    Like i said its probbaly not my problem but its thought provoking
    BornAgainSteama likes this.
  16. bara

    bara Well-Known Member

    I would like to add the getting COLD decreases my nausea,and I have no desire for hot showers. In fact, when I start to heat up my nausea comes on strong, I then have to turn up the AC, or go outside and cool down. the cap cream on the stomach does seem to help minorly. Less so inside the stomach.

    This, to me seems to strengthen the theories on heat regulation( and the processes behind it) at the main cause. I have the same problem, only in reverse.

    The last time I used weed regularly, I was on the keto diet and smoked heavily before doing very difficult hot yoga, maybe the reason why I am the oppposite of everyone else. That is when it started, shortly after that.

    I have similar symptoms as you. Bloating, constipation, and eventual nasua. You can keep playing with it as I did, but I'm on my second week now and it still hasn't cleared up completely. Some people seem to be able to manage it, I fear I am not one of them.

    According to wiki,

    The use of antipsychotics, such as haloperidol and olanzapine, have provided complete relief of symptoms in case-reports.


    Can anyone confirm this?
    Last edited: Nov 19, 2018
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  17. BornAgainSteama

    BornAgainSteama I'm proud to be a stoner, yes I am.

    I do not believe you have CHS (at least yet). To get a CHS diagnosis you will have the following symptoms.
    1. Severe nausea, cold sweats, and it comes on like a train. Very strong nausea.
    2. intractable vomiting or hyperemisis that can last for many hours. From my personal experience I have never felt more nauseated or vomited more violently and the funny thing was only one thing helped me feel any kind of relief at all...
    3. HOT baths! fuck showers! HOT baths and the hotter the better was the only thing that works to ease up for a few minutes but you can't lay in a hot tub forever. When you get out and begin to cool the vomiting hits you again full power. Now the interesting thing is I have never liked hot baths, never. In fact I have always avoided hot tubs they make me feel awful. So I was surprised as anyone to experience first, the extreme urge for a hot bath, then doing it repeatedly for relief, which worked a little.
    4. a real cannabis lovers habit, like everyday
    As far as one's own experience people with CHS with have some kind of mixture of this list of symptoms. Everyone pukes but not for 12 hours. If this happens you need to go to the emergency room.

    emergency room anecdotal evidence

    Your list of medications that can help is what I am also familiar with. In the U.S. because cannabis federally illegal there is not the study it deserves and it gets no funding so all we have is emergency room anecdotal evidence which is getting better because smart doctors have a clue now how to treat CHS. In fact if you show up unable to stop vomiting CHS is now a doctors first suspicion.

    if you in fact have CHS

    The most important thing to remember is to do everything you can to NOT let the vomiting cycle begin because if you have CHS your body has forgotten how to stop vomiting and you are in for a helluva ride. I promise you this 100%.


    Peace, and hope you do not experience this.


    1) Severe nausea, cold sweats, and it comes on like a train. Very strong nausea.

    This is the first and only warning sign I personally got...but it is a doozy! I have had about 5 very violent CHS attacks and I seriously wanted to die everytime. You will NEVER forget this hardcore nausea. I would compare it to an anaphylactic shock reaction...it will bring you to your knees to worship the white porcelain god longer than you ever have.

    The post above hits everything in an accurate and clear summary that will give you some idea if you really have CHS or are on your way....much about CHS is not yet understood. So it may have more than one face, but for now I am sticking to the most common type of CHS experience.

    Good luck my friends...If you haven't gone through what I describe you don't have all the symptoms of CHS which is a great thing!

    Last edited: Nov 20, 2018
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  18. BornAgainSteama

    BornAgainSteama I'm proud to be a stoner, yes I am.

    Sad news for me. CHS has raised it's ugly head once again in my life since my last post I have been experiencing unrelenting nausea on a daily basis, all day. Of course the only thing that has given me relief are hot baths which I am more than tired of.

    This time things are different in that although I have the urge to vomit I have not, but constant severe nausea is more than I can any longer take. So I have made the decision to completely quit cannabis 100%. I have not used cannabis for two days (wow) and today I still have the nausea but it is very mild so a hot was in order and made me feel better.

    From all I have read on and studied on CHS this is the only solution to end this horrible cycle.

    I hate to say this but if anyone else is suffering from intense nausea and/or vomiting it is more likely than not that you will have to discontinue use of cannabis.

    Good luck to anyone struggling with this strange painful condition.

    Peace out.
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  19. Abysmal Vapor

    Abysmal Vapor Shaman of The Pyramid of Orlin'Malah

    7th heaven - 666th pit (EU)
    So sad to hear about your condition and also for the rest of the guys. I have a friend who had a battle with it for a while.
    He claims that aromatherapy and also quiting it for a long period of time was key to his relief.
    I just googled out appropriate oils for Nausea ,probably you can try them.. Maybe vape some mint or lavender and see if that helps too. My friend shared that he still gets sick from very powerful flowers,her prefers weak ones and enriches them with terps if needed,and also uses just ocassionally not giving them chance to build up inside him up to irrirating levels.
    I found it weird that hot baths relieve nausea,i dont know this condition from inside,but when nauseus i prefer the coldness,maybe it really has to do something with the serotonin cycle.
    It really pains me that something that is such a good problem solver for me causes pains and issues for other people and cannot really imagine what will i do if i have to give up on those benefits.
    Hoping that you will get relief to your condition ASAP .


    Aromatherapy has long been recognized as a safe and effective treatment for nausea. There are a variety of scented oils available to help ease rumbling tummies and keep you from making mad dashes to the bathroom.

    Aromatherapy is particularly appropriate for women with morning sickness, who need to be careful about what kinds of medications they ingest. It’s also a great option for those who are undergoing nausea-inducing cancer treatments, since they are not a drug and won’t cause undesirable side effects.

    You can use aromatherapy oils straight by putting a few drops on a tissue or hanky and placing it over your nose. Alternately, there are a number of aromatherapy products available, including:

    • Candles
    • Incense
    • Nasal plugs
    • Misters
    • Diffusers
    • Herbal wraps
    There are many types of scented oil available. Experiment with several types (and possibly even blends) to see what works best for you. Here are a few of the best scented oils for nausea:

    • Peppermint. Perhaps the most commonly used oil for nausea. Peppermint oil offers fast relief. As a bonus, it can give you energy and relieve headaches, too.
    • Orange. Orange oil is effective for nausea caused by digestive problems. It can also help with other digestive issues like flatulence and constipation. In addition to relieving nausea, orange oil is known as a stress reliever. Orange oils come in sweet orange and Mandarin varieties. Both are effective for relieving nausea.
    • Petitigrain. Petitigrain is effective for nausea caused by morning sickness, especially when blended with other essential oils. It also helps with insomnia.
    • Ginger. Everyone knows about drinking ginger ale for nausea, but the essential oils are even more effective. Used alone or blended with orange oil, it adds some pep to your step while relieving your nausea symptoms.
    • Lavender. Widely regarded as one of the best essential oils for morning sickness. It can be used like other essential oils or added to a hot compress on the tummy. In addition to relieving nausea, it can help calm frazzled nerves.
    • Spearmint. Spearmint oil relieves nausea and can be used alone or blended with lavender. In addition to relieving nausea, it helps to reduce fatigue. It is also effective against headaches (including migraines) and as a stress reliever.
    These are just a few of the many essential oils which can be used to treat nausea. It’s a good idea to have a variety of essential oils on hand to deal with nausea. Use invigorating oils like peppermint, ginger, and spearmint in the morning when you need to get up and get going with your day. Use soothing oils like lavender when nausea strikes later in the day to help you get some rest.
  20. chris 71

    chris 71 Well-Known Member

    Sorry to hear of your troubles steama , i too have been feeling more and more sick everytime i vape my guts are soo messed up .

    I stopped for a few days but still feeling nausea. I have been reading lots about this as well and i keep coming accross the capsaicin cream thing again and again . i know you are feeling like crap but since your reporting that you are already doing the hot water thing if you get a chance maybe you can try the cream and report back if it helped at all ?
    Anyway i hope it passes quick for you man
  21. BornAgainSteama

    BornAgainSteama I'm proud to be a stoner, yes I am.

    Thank for your compassion but sadly I am finished with cannabis.
  22. justcametomind

    justcametomind IT'S TIME!

    I have suffered from CHS years ago .
    That happens to me when my tolerance rises to high level for prolonged periods of time.
    Other than hot baths and pepper, what has been crucial to me was physical activity . That way you burn cannabis metabolites out of your system. Since I had introduced the gym in my life as a 3 times a week routine, CHS has since to be seen again. I'm lucky because not all users have the ability to do that because of disabilities.
    Last edited: Dec 24, 2018
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  23. BornAgainSteama

    BornAgainSteama I'm proud to be a stoner, yes I am.

    Update on quitting cannabis due to CHS. I must say beyond any doubt this was the best course of action. Of course as most of us know that quitting cannabis is not that difficult especially if you have ever practiced t-breaks. For me quitting cannabis is one day and done, completely cold turkey with no issues at all.

    All symptoms of CHS have ceased and I feel like a million dollars. If you suffer from severe CHS I highly recommend quitting with all my heart. Quitting is worth not suffering with CHS, period.

    If you are on the fence about what to do get off the fence and just quit. It is not that hard.

    I am still a fervent advocate for cannabis but over the years I arrived at a place where I can no longer partake. If you do not suffer from CHS enjoy the herb by all means. I have loved her almost my entire life.

    Take care, and take care of yourselves FC friends.

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  24. invertedisdead

    invertedisdead High Standards

    The Full Spectrum
    Do you think you would respond better after the body purges itself of exogenous cannabinoids a while longer? Or do the symptoms flare up again a few months later?
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  25. justcametomind

    justcametomind IT'S TIME!

    I had similar feelings when I quit for the same reason. Quitting a habit gives you a sense of empowerment, like when we quit tobacco or combustion. It's perfectly fine if you feel like cannabis is not essential to life.
    @invertedisdead ime the symptoms flare up when your tolerance is very high, with constant and heavy use of vaporization. If you can take cannabinoids out of your system you don't fall into CHS, this is done by physical activity or directly leaving those cannabinoids out, by partaking less or stopping.
    When I cross the line between heavy use and CHS and start to feel the symptoms, I feel like stoner sloth with added nausea. Mind is blurry, I'm super lazy, my senses are made exacerbated by cannabinoids, I can't stand what I usually don't, but 10 times harder (noises, people, pain). Cold water starts to be unbearable. Cold weather too.
    No wonder @BornAgainSteama wants to feel a million dollar from now on. It's nice experimenting again with different rewards than cannabis only: better sleep, short memory slowly returning back to normal, getting more things done.:myday:

    The first time I experienced CHS I quit as well. I came back to cannabis use a few years later with the not so obvious persuasion that sedentary life leads to unhealthy life. And no gym+lots of vaping=CHS, sooner or later.

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