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Micro-dosing

howie105

Well-Known Member
Started new meds, vaping weed made me have straight up panic attacks which is devastating. (On a regular dose)

Tried a microdose...'literally fuck all' in the vapcap m with ti tip - Possibly 0.001 or less?

I don't get a racing heart but can enjoy my green again after a long t break.

Happy days. (Plus i've saved an inordinate amount of money! Win win!!)

What scale are you using to get measurements in the .001g range? I been getting by with a cheap digital but its reached its limit on the loads I am trying to measure, I would really appreciate a link too if you have one. Thanks
 
howie105,
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analytika

Well-Known Member
Hello, i am down from 500mg to 200mg a day. I use the mighty. I really love this device. How ever when i try to heat 50mg it gets a bit inefficient imo. I use capsules, i use liquid pads. I even build some stuff out of screens. it just does not feel right to me at these low dosses.

Is there someone that could suggest a vape device for very small doses? 50mg is a start for me. i want to go lower and lower.

Does not matter if its portable or not. I do not like the idea of the vapcap. However if people really suggest it here i might give it a try.

i love the idea of filtering it through water. never done it tho.

Have a great day!
Not inefficient as in you don't fully extract.
Just slow, when microdosing with pods and liquid pads

You can't really have a short session with the Mighty, when microdosing. You still have to take 4 to 6 full, generous draws. Where you'd be fully extracted at 2-3 on a Dynavap.

If you're in the mood to slow down, want smooth, velvety pulls, nothing harsh, the mighty is a pleasure for microdosing.

Do I very often? No.
 
analytika,

MegaMan2k

Well-Known Member
Anyone here microdosing with dabs?,
Im getting back to microdosing, after over-dosing for a long time lol.

I find it "possible" to microdose with dabs, but i really need to pay much attention to the amounts, since i can ruin that tolerance in one hit
 
MegaMan2k,

analytika

Well-Known Member
Anyone here microdosing with dabs?,
Im getting back to microdosing, after over-dosing for a long time lol.

I find it "possible" to microdose with dabs, but i really need to pay much attention to the amounts, since i can ruin that tolerance in one hit
Key is willingness to abstain for a bit if you miscalculate.
 
analytika,

MegaMan2k

Well-Known Member
Yea im on a t-break right now, to really get my tolerance all the way down before beginning xD
its just
Micro dosing with herbal cannabis feels easier, thats what i did last time i tried out microdosing

i want to take the pure smooth hits from dabbing with me into microdosing this time, if that makes any sense.. (not that herbal cannabis is not pure and smooth, i love herbal, and will be going back to herbal if i have too little success with microdosing with concentrates)

maybe weigh out single dabs, i would love to be able to get the exact same mg of cannabinoids/terps at the exact same time every day, staying consistently medicated.

I have definitely come to a point where i dont need that high-dosage pain numbing amounts on the daily any longer. (Not that anything is wrong with that / when i was in pain i was doing the same)

I feel better mentally with just being lit up by a small dosage that inspires me, better at interacting with people and so on. (but only if i already have my tolerance cranked down for that small dosage)
 

ronads

Well-Known Member
What scale are you using to get measurements in the .001g range? I been getting by with a cheap digital but its reached its limit on the loads I am trying to measure, I would really appreciate a link too if you have one. Thanks

Hey dude! I should have said that was a bit of a guess. I have a scale that goes to 0.01 and I tried to weigh it with absolutely no results.

I put on more and more and more to see how much it would take to get to 0.01 and it was a hell of a lot more.

If you do a fine grind I’d say one or two “flakes”.
 

nosmoking

Just so Dab HAppy!
I know there have been plenty of discussions about what actually constitutes a "micro-dose". I am not trying to rehash that discussion however I did want to point out something I stumbled upon yesterday. Dr. James Fadiman' explanation of microdosing in the Netflix docu "Take Your Pills". At about the 1 hour and 11 minute mark he explains that a micro dose is 1/10th to 1/20th of a full dose and you can expect no psychedelic effects. At this point of the focus they are talking about LSD and mushrooms and pills, not cannabis however I would imagine this is the more common explanation for micro-dosing in regard to the medical field. Really neat stuff about the micro-dosing of LSD and mushrooms.
 

MegaMan2k

Well-Known Member
Yes indeed, I wonder this perspective at times : A micro dose to me, could be enough to over-saturate someone else's system / receptors .
Since we are all so very different, it is going to be hard to determine a universal micro-dose i guess,
 

analytika

Well-Known Member
I know there have been plenty of discussions about what actually constitutes a "micro-dose". I am not trying to rehash that discussion however I did want to point out something I stumbled upon yesterday. Dr. James Fadiman' explanation of microdosing in the Netflix docu "Take Your Pills". At about the 1 hour and 11 minute mark he explains that a micro dose is 1/10th to 1/20th of a full dose and you can expect no psychedelic effects. At this point of the focus they are talking about LSD and mushrooms and pills, not cannabis however I would imagine this is the more common explanation for micro-dosing in regard to the medical field. Really neat stuff about the micro-dosing of LSD and mushrooms.
The technical definition of microdosing is to dose so low there are no perceptible effects. "Sub clinical". That's not how we all tend to use the term here, I believe, because cannabis' effects are perceptible (though not necessarily satisfactory) at almost any dose. Not everyone agrees.
 

howie105

Well-Known Member
Hey dude! I should have said that was a bit of a guess. I have a scale that goes to 0.01 and I tried to weigh it with absolutely no results.

I put on more and more and more to see how much it would take to get to 0.01 and it was a hell of a lot more.

If you do a fine grind I’d say one or two “flakes”.

Thanks Ronads, looks like we are in the same boat.
 
howie105,

florduh

Well-Known Member
Yea im on a t-break right now, to really get my tolerance all the way down before beginning xD
its just
Micro dosing with herbal cannabis feels easier, thats what i did last time i tried out microdosing

i want to take the pure smooth hits from dabbing with me into microdosing this time, if that makes any sense.. (not that herbal cannabis is not pure and smooth, i love herbal, and will be going back to herbal if i have too little success with microdosing with concentrates)

maybe weigh out single dabs, i would love to be able to get the exact same mg of cannabinoids/terps at the exact same time every day, staying consistently medicated.

I have definitely come to a point where i dont need that high-dosage pain numbing amounts on the daily any longer. (Not that anything is wrong with that / when i was in pain i was doing the same)

I feel better mentally with just being lit up by a small dosage that inspires me, better at interacting with people and so on. (but only if i already have my tolerance cranked down for that small dosage)


I "microdose" with oil pens/cartridges all the time. Just take one small pull at a lower wattage, then go about your day.
 

EverythingsHazy

Well-Known Member
I know there have been plenty of discussions about what actually constitutes a "micro-dose". I am not trying to rehash that discussion however I did want to point out something I stumbled upon yesterday. Dr. James Fadiman' explanation of microdosing in the Netflix docu "Take Your Pills". At about the 1 hour and 11 minute mark he explains that a micro dose is 1/10th to 1/20th of a full dose and you can expect no psychedelic effects. At this point of the focus they are talking about LSD and mushrooms and pills, not cannabis however I would imagine this is the more common explanation for micro-dosing in regard to the medical field. Really neat stuff about the micro-dosing of LSD and mushrooms.
That’s what I was saying over a year ago, and I was attacked. Lol

I think people here like to say they are microdosing, because it feels good to believe that, whether it’s true or not. It defeats the purpose of the term, though, and makes actual microdosing discussion difficult to differentiate from just having a low tolerance and using small doses.
 
EverythingsHazy,

MegaMan2k

Well-Known Member
That’s what I was saying over a year ago, and I was attacked. Lol

I think people here like to say they are microdosing, because it feels good to believe that, whether it’s true or not. It defeats the purpose of the term, though, and makes actual microdosing discussion difficult to differentiate from just having a low tolerance and using small doses.


I understand, if this is the definition of microdosing, then thats not what im trying to achieve-

Im not sure i can agree with the "feels good" part, i dont see why?


To me, microdosing cannabis is about modulating my system as much as possible with as little as possible,.

edit, I can see how this contradicts the definition of microdosing already lol lol lol im sorry
 

analytika

Well-Known Member
Try using the smallest
I just received this scale from dhgate ; https://www.dhgate.com/product/0-001g-20g-mini-pocket-jewelry-diamond-weight/231736320.html

Im guessing its not 100% accurate at this price point- but its got one additional decimal
Used such a scale a few times. But learned only as much as you could from some of the images of various weighed amounts of material posted here. And once I had a feel for it, and a better association between amount, effect and tolerance, never took the scale out again.
 
analytika,

MinnBobber

Well-Known Member
Microdosing, or micro-dosing, is a technique for studying the behaviour of drugs in humans through the administration of doses so low ("sub-therapeutic") they are unlikely to produce whole-body effects, but high enough to allow the cellular response to be studied.
As mentioned, this term is now used with magic mushrooms or psychedelics for one new vein of microdosing.

The real/original microdosing definition relates to a more formal aspect, "phase zero" on drug development--before clinical phase 1, to to predict whether a drug is viable for the next phase of testing. Human Microdosing aims to reduce the resources spent on non-viable drugs and the amount of testing done on animals. These amounts are typically 1/10 of the normal dose.

So the recent psychedelic explorations stole the term, which is fine by me as language is alive. They use small amounts for their experiments.

IMO, many on here do microdose---take small amounts (like 1/10 a normal dose) and they do not have whole body effects.
The dose is high enough to get cellular response yet not a whole-body effect.

I'm still calling it microdosing cannabis.
Just like a "dab" of Bryllcream will do ya' evolved into a current dab definition, microdosing is different in different contexts.

Another definition of it is:
Less commonly, the term "microdosing" is also used to refer to precise dispensing of small amounts of a drug substance. For example, a 0.012 g dose of cannabis???

If 1/10 of a dose of magic mushrooms is microdosing, so is a small dose of cannabis.

"Micro-dosing" = different definitions for different arenas, from formal new drug studies to recent psychedelic use to cannabis use.

It's the evolution of language, whether you like it or not. :)
 

EverythingsHazy

Well-Known Member
I understand, if this is the definition of microdosing, then thats not what im trying to achieve-

Im not sure i can agree with the "feels good" part, i dont see why?


To me, microdosing cannabis is about modulating my system as much as possible with as little as possible,.

edit, I can see how this contradicts the definition of microdosing already lol lol lol im sorry
Haha, no problem. That's perfectly fine. True microdosing isn't for everyone.

I suspect that it feels good to believe that you microdose, because it carries less of a "pothead" connotation, and more of a medicinal one , when you are "microdosing".
I guess I don't technically micro-dose.

I do use the minimum effective dose.
Are you considering the smallest effective dose to be the smallest dose that produces perceptible results? If not, could you clarify that? I would consider Cannabis medically effective well below the perceptible dose levels.
Microdosing, or micro-dosing, is a technique for studying the behaviour of drugs in humans through the administration of doses so low ("sub-therapeutic") they are unlikely to produce whole-body effects, but high enough to allow the cellular response to be studied.
As mentioned, this term is now used with magic mushrooms or psychedelics for one new vein of microdosing.

The real/original microdosing definition relates to a more formal aspect, "phase zero" on drug development--before clinical phase 1, to to predict whether a drug is viable for the next phase of testing. Human Microdosing aims to reduce the resources spent on non-viable drugs and the amount of testing done on animals. These amounts are typically 1/10 of the normal dose.

So the recent psychedelic explorations stole the term, which is fine by me as language is alive. They use small amounts for their experiments.

IMO, many on here do microdose---take small amounts (like 1/10 a normal dose) and they do not have whole body effects.
The dose is high enough to get cellular response yet not a whole-body effect.

I'm still calling it microdosing cannabis.
Just like a "dab" of Bryllcream will do ya' evolved into a current dab definition, microdosing is different in different contexts.

Another definition of it is:
Less commonly, the term "microdosing" is also used to refer to precise dispensing of small amounts of a drug substance. For example, a 0.012 g dose of cannabis???

If 1/10 of a dose of magic mushrooms is microdosing, so is a small dose of cannabis.

"Micro-dosing" = different definitions for different arenas, from formal new drug studies to recent psychedelic use to cannabis use.

It's the evolution of language, whether you like it or not. :)
If language evolves to change the meaning of "microdose" from a medical/scientific one to casual one, how will we refer to what is currently medical microdosing? Do you have any ideas? It wouldn't make sense to just lose clarity on the issue.
 
EverythingsHazy,

MegaMan2k

Well-Known Member
Haha, no problem. That's perfectly fine. True microdosing isn't for everyone.

I suspect that it feels good to believe that you microdose, because it carries less of a "pothead" connotation, and more of a medicinal one , when you are "microdosing".

.

If we looked at MY past dosages i could very easily be on 10-20x "less" now, xD

I think that is more of a prohibition based stigma with the pothead connotation there, since medical use could call for many different dosages, even very high dosages on the daily. So that would be a medical-pothead lol.. But i get where you are coming from ofc.

Also : I see that there is a bunch of people with ADHD and the likes that is able to replace their medications by doing what they themselves describe as microdosing, but it would properly not meet your scientific/medical requirements for true microdosing either, since they are going for that slight buzz where you are between high and sober,
 

analytika

Well-Known Member
Haha, no problem. That's perfectly fine. True microdosing isn't for everyone.

I suspect that it feels good to believe that you microdose, because it carries less of a "pothead" connotation, and more of a medicinal one , when you are "microdosing".

Are you considering the smallest effective dose to be the smallest dose that produces perceptible results? If not, could you clarify that? I would consider Cannabis medically effective well below the perceptible dose levels.

If language evolves to change the meaning of "microdose" from a medical/scientific one to casual one, how will we refer to what is currently medical microdosing? Do you have any ideas? It wouldn't make sense to just lose clarity on the issue.
Here's a simple definition that captures what microdosing means to me:

this ==> A dose at which I do not develop tolerance at my preferred frequency of administration. <== this

If you need a little more every time, or would need less if you took a break, you're not microdosing.

One implication: the size of a microdose depends on your frequency.

If you overindulge, you can compensate by waiting longer until your next session.

Do I microdose? Mostly.
 
Last edited:

MinnBobber

Well-Known Member
If language evolves to change the meaning of "microdose" from a medical/scientific one to casual one, how will we refer to what is currently medical microdosing? Do you have any ideas? It wouldn't make sense to just lose clarity on the issue.
...............................................................................................................
Absent a new word, like "canna-microdosing", I'm ok with microdosing having a slightly different meaning for different contexts (1. the original formal "phase-zero" for formal drug development protocol 2. the micro ingestion of psychedelics like magic mushrooms for self awareness/ enhancing one's self and 3. small doses of cannabis )

I'm a fan of Dr. Dustin Sulak, a very well respected "Cannabis medical Dr".
His microdosing defin is:
"Cannabis microdosing, taking a non- or slightly psychoactive dose for the purpose of improving heath and productivity, has been gaining popularity."
He even includes a slightly psychoactive dose.....

Does intent enter in? I microdose as a "health supplement", IMO the absolute best health supplement in the world :)

Thinking back 40 years, when I'm not sure what I had for lunch yesterday :), and my experience with magic mushrooms:
I'd think that a 1/10 normal dose (microdose) of 'shrooms produces more mental/physical effects than a 1/10 microdose of cannabis.
Anyone have a 'shroom supply and want to experiment and report back?

And since cannabis is not "one size fits all/ same for everyone": for someone that normally takes a huge daily dose , like Steve DeAngelo from Harborside, his microdose might be a one month supply for my use. I can't find it now but in an interview he was asked about his daily use and I just remember going, "holy crap, good thing he owns the dispensaries" as
it was huge mg amount!!!

No microdose yet today for me---better get with it ;)
 

florduh

Well-Known Member
Are you considering the smallest effective dose to be the smallest dose that produces perceptible results? If not, could you clarify that? I would consider Cannabis medically effective well below the perceptible dose levels.

I'll occasionally use amounts that don't cause a perceptible result. But in generally my "minimum effective dose" is the smallest amount that does cause a perceptible result.
 

MegaMan2k

Well-Known Member
abstaining for 2 full days bringing down my tolerance. however i accidently take one too large dab and i feel my tolerance is just instantly back up there.
Maybe I need to abstain for more than just a couple of days? before beginning,
 
MegaMan2k,
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